Evidence map›Paper›PMID 35861369›Full record

ArticleCancer medicine2023

Genetic variants in RNA m

Silu Chen, Xiangming Cao, Shuai Ben, Lingjun Zhu, Dongying Gu, Yuan Wu, Shuwei Li, Qiang Yu

Open access · goldAbstract read
In one paragraph

Article in Cancer medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Detection, molecular function and mechanisms of m5C in cancer.Clinical and translational medicine · 2025
    Review
  3. Review
  4. Genetic variants in RNA mCancer medicine · 2023
    Article
  5. Vital roles of mFrontiers in immunology · 2023
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 2 countries.

Silu ChenDepartment of Gastroenterology, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, Jiangsu, China.
Xiangming CaoDepartment of Oncology, The Affiliated Jiangyin Hospital of Southeast University Medical College, Jiangyin, China.
Shuai BenDepartment of Genetic Toxicology, The Key Laboratory of Modern Toxicology of Ministry of Education, Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, China.
Lingjun ZhuDepartment of Oncology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.ORCID 0000-0001-8033-1528
Dongying GuDepartment of Oncology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Yuan WuDepartment of Medical Oncology, Jiangsu Cancer Hospital, Jiangsu Institute of Cancer Research, The Affiliated Cancer Hospital of Nanjing Medical University, Nanjing, China.
Shuwei LiDepartment of Genetic Toxicology, The Key Laboratory of Modern Toxicology of Ministry of Education, Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, China.ORCID 0000-0002-6142-0573
Qiang YuDepartment of Gastroenterology, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, Jiangsu, China.
Ministry of Education · KRJiangsu Cancer Hospital · CNJiangsu Province Hospital · CNJiangyin People's Hospital · CNNanjing Medical University · CNSuzhou Municipal Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundColorectal cancer is one of the most common malignant digestive tract tumors with a poor prognosis. RNA 5-methylcytosine (m

methodsWe investigated the association between candidate single nucleotide polymorphisms (SNPs) in 13 m

resultsWe identified that two SNPs in YBX1 were associated with OS after chemotherapy (HR = 1.43, p = 0.001 for rs10890208; HR = 1.36, p = 0.025 for rs3862218). A striking dose-response effect between NRA and OS after chemotherapy was found (p

conclusionOur study indicates that genetic variants in m

Indexed as

Colorectal NeoplasmsAntineoplastic Combined Chemotherapy ProtocolsHumansOxaliplatinPolymorphism, Single NucleotidePrognosisRNARNA, MessengerOxaliplatinRNARNA, Messengerchemotherapycolorectal cancergenetic variantssurvival

Identifiers

PMID35861369
PMCPMC9883553
OpenAlexW4286110822

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.