Evidence map›Paper›PMID 35861249›Full record

ArticleThe International journal of eating disorders2022

Characterizing changes in obsessive-compulsive symptoms over the course of treatment for adolescent bulimia nervosa.

Erin E Reilly, Sasha Gorrell, Leigh Brosof, James Lock, Daniel Le Grange

Open access · greenAbstract read
In one paragraph

Article in The International journal of eating disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Observational
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Erin E ReillyDepartment of Psychiatry and Behavioral Sciences, University of California, San Francisco, California, USA.ORCID 0000-0001-9269-0747
Sasha GorrellDepartment of Psychiatry and Behavioral Sciences, University of California, San Francisco, California, USA.ORCID 0000-0002-8861-8547
Leigh BrosofDepartment of Psychiatry and Behavioral Sciences, University of California, San Francisco, California, USA.ORCID 0000-0002-9254-1992
James LockDepartment of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California, USA.ORCID 0000-0002-5169-1484
Daniel Le GrangeDepartment of Psychiatry and Behavioral Sciences, University of California, San Francisco, California, USA.ORCID 0000-0001-7293-9496
University of California, San Francisco · USStanford University · USUniversity of Louisville · US

Funding

UCSD Leading the Advancement of Underrepresented Neuroscientists for Change (LAUNCH) Faculty Development ProgramR25NS117367 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Victoria B Risbrough, Joann Trejo · 2020 to 2026
$1.6M
Neural Correlates of Reinforcement Learning Specific to Hyperactivityin Adolescent Anorexia NervosaK23MH126201 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GORRELL, SASHA CATHERINE · 2021 to 2025
$848k
NIMH NIH HHS K23 MH126201NIMH NIH HHS R01-MH-079978NIMH NIH HHS R01-MH-079979NINDS NIH HHS R25 NS117367
6 · The paper itself

Abstract

objectiveData suggest that obsessive-compulsive (OC) symptoms are commonly observed in adolescents with eating disorders and predict poorer treatment response. Further, emerging data among adults suggest that changes in OC symptoms relate to changes in eating disorder symptoms across treatment. Given evidence that early invention decreases risk for protracted illness, evaluating processes that may relate to treatment response will be useful in increasing the effectiveness of existing interventions. Therefore, the current investigation explored changes in general and eating disorder-specific OC symptoms throughout family-based treatment (FBT) and cognitive behavioral therapy (CBT) for bulimia nervosa (BN), as well as associations among these changes and eating disorder outcomes at follow-up.

methodParticipants (N = 110) received 18 sessions of FBT or CBT and completed measurements of general and eating disorder-specific OC symptoms at baseline, end-of-treatment, and 6- and 12-month follow-up.

resultsMultilevel models indicated that across both treatments, there was no change in general OC symptoms, whereas all eating disorder-related OC symptoms decreased over treatment and follow-up. Exploratory analyses indicated that lower severity in discharge eating-disorder-specific OC symptoms contributed to lower eating pathology at follow-up. DISCUSSION: Together, findings support the efficacy of both FBT and CBT in helping to reduce eating disorder-specific OC symptoms and suggest that adjunctive intervention may be required for ameliorating general OC symptoms in this population. PUBLIC SIGNIFICANCE: BN is associated with significant increases in mortality and societal cost, and there is a pressing need for innovations within available treatments for young people with this disorder. In the current study, we explore the extent to which existing evidence-based treatments for adolescent BN are effective in targeting obsessive-compulsive symptoms, a known predictor of treatment response and common co-morbidity in this population.

Indexed as

Bulimia NervosaCognitive Behavioral TherapyFeeding and Eating DisordersObsessive-Compulsive DisorderAdolescentAdultComorbidityHumansadolescentbulimia nervosacognitive-behavioral therapyfamily-based treatmentobsessive-compulsive symptoms

Identifiers

PMID35861249
PMCPMC9869712
OpenAlexW4286016529

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.