Evidence map›Paper›PMID 35861144›Full record

ArticleChemistry (Weinheim an der Bergstrasse, Germany)2022

Enhancing the Peroxygenase Activity of a Cofactor-Independent Peroxyzyme by Directed Evolution Enabling Gram-Scale Epoxide Synthesis.

Marie-Cathérine Sigmund, Guangcai Xu, Eleonora Grandi, Gerrit J Poelarends

Open access · hybridAbstract read
In one paragraph

Article in Chemistry (Weinheim an der Bergstrasse, Germany), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Empowering Precision C-H Functionalization: Advances in Peroxygenase Engineering.Angewandte Chemie (International ed. in English) · 2026
    Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Marie-Cathérine SigmundDepartment of Chemical and Pharmaceutical Biology, University of Groningen, Antonius Deusignlaan 1, 9713 AV, Groningen, The Netherlands.
Guangcai XuDepartment of Chemical and Pharmaceutical Biology, University of Groningen, Antonius Deusignlaan 1, 9713 AV, Groningen, The Netherlands.
Eleonora GrandiDepartment of Chemical and Pharmaceutical Biology, University of Groningen, Antonius Deusignlaan 1, 9713 AV, Groningen, The Netherlands.
Gerrit J PoelarendsDepartment of Chemical and Pharmaceutical Biology, University of Groningen, Antonius Deusignlaan 1, 9713 AV, Groningen, The Netherlands.ORCID http://orcid.org/0000-0002-6917-6368
University of Groningen · NL

Funding

Horizon 2020 Framework Programme 723390Nederlandse Organisatie voor Wetenschappelijk Onderzoek 724.016.002
6 · The paper itself

Abstract

Peroxygenases selectively incorporate oxygen into organic molecules making use of the environmentally friendly oxidant H

Indexed as

AldehydesEpoxy CompoundsMixed Function OxygenasesOxidantsOxygenPharmaceutical PreparationsWaterAldehydesEpoxy CompoundsMixed Function OxygenasesOxidantsOxygenperoxygenasePharmaceutical PreparationsWatercofactor-independentdirected evolutionepoxidationperoxygenaseperoxyzyme

Identifiers

PMID35861144
PMCPMC9804992
OpenAlexW4286494024

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.