Evidence map›Paper›PMID 35860755›Full record

ArticleMolecular genetics and metabolism reports2022

A new pathogenic POLG variant.

S Nicholas Russo, Ekta G Shah, William C Copeland, Mary Kay Koenig

Erratum issuedOpen access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular genetics and metabolism reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. [Advances in the molecular genetics of nuclear gene mutations causing pediatric mitochondrial cardiomyopathy].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2026
    Pooled it
  2. Progressive Axonal Neuropathy and Cerebellar Ataxia Associated with Homozygous PathogenicTremor and other hyperkinetic movements (New York, N.Y.) · 2026
    Article
  3. TheGenes · 2025
    Article
  4. The Y831C Mutation of theBiomedicines · 2023
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

S Nicholas RussoThe University of Texas McGovern Medical School, Department of Pediatrics, Division of Child and Adolescent Neurology, Houston, TX, USA.
Ekta G ShahThe University of Texas McGovern Medical School, Department of Pediatrics, Division of Child and Adolescent Neurology, Houston, TX, USA.
William C CopelandMitochondrial DNA Replication Group, Genome Integrity and Structural Biology Laboratory, National Institute of Health, Research Triangle Park, NC, USA.
Mary Kay KoenigThe University of Texas McGovern Medical School, Department of Pediatrics, Division of Child and Adolescent Neurology, Houston, TX, USA.
The University of Texas Health Science Center at Houston · USNational Institute of Environmental Health Sciences · US

Funding

Molecular Characterization Of The Mitochondrial Dna PolymeraseZIAES065078 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI COPELAND, WILLIAM · 2009 to 2025
$25.4M
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Alpers-Huttenlocher syndromeDNA polymerase gammaMitochondriaMitochondrial depletionPOLG syndrome

Identifiers

PMID35860755
PMCPMC9289853
OpenAlexW4285082179

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.