Evidence map›Paper›PMID 35860728›Full record

ArticleFrontiers in medicine2022

Widefield Optical Coherence Tomography in Pediatric Retina: A Case Series of Intraoperative Applications Using a Prototype Handheld Device.

Thanh-Tin P Nguyen, Shuibin Ni, Guangru Liang, Shanjida Khan, Xiang Wei, Alison Skalet, Susan Ostmo, Michael F Chiang, Yali Jia, David Huang and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 25 citations in OpenAlex.

  1. Utility of handheld optical coherence tomography imaging in the surgical management of preterm infants with advanced retinopathy of prematurity.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Article
  2. Article
  3. Imaging infants and children with investigational handheld optical coherence tomography with widefield lens: a pilot study.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Article
  4. Article
  5. Article
  6. Widefield OCT angiography.Progress in retinal and eye research · 2025
    Review
  7. Review
  8. New Directions for Ophthalmic OCT - Handhelds, Surgery, and Robotics.Translational vision science & technology · 2025
    Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Panretinal Optical Coherence Tomography.IEEE transactions on medical imaging · 2023
    Article
  14. Review
  15. Review
  16. Review
  17. Optical coherence tomography imaging of the peripheral retina.Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Thanh-Tin P NguyenCasey Eye Institute, Oregon Health and Science University, Portland, OR, United States.
Shuibin NiCasey Eye Institute, Oregon Health and Science University, Portland, OR, United States.
Guangru LiangCasey Eye Institute, Oregon Health and Science University, Portland, OR, United States.
Shanjida KhanCasey Eye Institute, Oregon Health and Science University, Portland, OR, United States.
Xiang WeiCasey Eye Institute, Oregon Health and Science University, Portland, OR, United States.
Alison SkaletCasey Eye Institute, Oregon Health and Science University, Portland, OR, United States.
Susan OstmoCasey Eye Institute, Oregon Health and Science University, Portland, OR, United States.
Michael F ChiangNational Eye Institute, National Institutes of Health, Bethesda, MD, United States.
Yali JiaCasey Eye Institute, Oregon Health and Science University, Portland, OR, United States.
David HuangCasey Eye Institute, Oregon Health and Science University, Portland, OR, United States.
Yifan JianCasey Eye Institute, Oregon Health and Science University, Portland, OR, United States.
J Peter CampbellCasey Eye Institute, Oregon Health and Science University, Portland, OR, United States.
Oregon Health & Science University · USNational Institutes of Health · US

Funding

Translational Core for Therapeutic and Diagnostic DevelopmentP30EY001792 · NEI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI AAKALU, VINAY · 1985 to 2025
$14.8M
Clinical and Genetic Analysis of Retinopathy of PrematurityR01EY019474 · NEI · OREGON HEALTH & SCIENCE UNIVERSITY · PI CAMPBELL, JOHN PETER · 2010 to 2020
$7.0M
Artificial Intelligence Assisted Panoramic Optical Coherence Tomography Angiography for Retinopathy of PrematurityR01HD107494 · NICHD · OREGON HEALTH & SCIENCE UNIVERSITY · PI John Peter Campbell, Yifan Jian · 2021 to 2026
$2.4M
Artificial intelligence assisted panoramic Optical Coherence Tomography Angiography for Retinopathy of PrematurityR01EY031331 · NEI · OREGON HEALTH & SCIENCE UNIVERSITY · PI CAMPBELL, JOHN PETER, JIAN, YIFAN · 2020 to 2020
$342k
NEI NIH HHS P30 EY001792NEI NIH HHS R01 EY019474NEI NIH HHS R01 EY031331NICHD NIH HHS R01 HD107494
6 · The paper itself

Abstract

Optical coherence tomography (OCT) has changed the standard of care for diagnosis and management of macular diseases in adults. Current commercially available OCT systems, including handheld OCT for pediatric use, have a relatively narrow field of view (FOV), which has limited the potential application of OCT to retinal diseases with primarily peripheral pathology, including many of the most common pediatric retinal conditions. More broadly, diagnosis of all types of retinal detachment (exudative, tractional, and rhegmatogenous) may be improved with OCT-based assessment of retinal breaks, identification of proliferative vitreoretinopathy (PVR) membranes, and the pattern of subretinal fluid. Intraocular tumors both benign and malignant often occur outside of the central macula and may be associated with exudation, subretinal and intraretinal fluid, and vitreoretinal traction. The development of wider field OCT systems thus has the potential to improve the diagnosis and management of myriad diseases in both adult and pediatric retina. In this paper, we present a case series of pediatric patients with complex vitreoretinal pathology undergoing examinations under anesthesia (EUA) using a portable widefield (WF) swept-source (SS)-OCT device.

Indexed as

handheld optical coherence tomographyoptical coherence tomographyoptical coherence tomography with angiographypediatric retinaretina

Identifiers

PMID35860728
PMCPMC9289179
OpenAlexW4283800395

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.