ArticleFrontiers in human neuroscience2022
Functional and Prognostic Assessment in Comatose Patients: A Study Using Somatosensory Evoked Potentials.
Article in Frontiers in human neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed, 10 citations in OpenAlex.
- Prognostic utility of somatosensory evoked potentials in supratentorial hemorrhage-induced prolonged disorders of consciousness.European journal of medical research · 2025Article
- Post-Coma Neurorehabilitation: Neurophysiological Assessment as an Additional Strategic and Essential Competence for the Physiatrist.Journal of personalized medicine · 2025Review
- Development of a nomogram for predicting the outcome in patients with prolonged disorders of consciousness based on the multimodal evaluative information.BMC neurology · 2025Article
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Authors and funding
6 authors at 4 institutions in 1 country.
Funding
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Abstract
Aim: The functional prognosis of patients after coma following either cardiac arrest (CA) or acute structural brain injury (ABI) is often uncertain. These patients are associated with high mortality and disability. N20 and N70 somatosensory evoked potentials (SSEP) are used to predict prognosis. We evaluated the utility of SSEP (N20-N70) as an early indicator of long-term prognosis in these patients. Methods: This was a retrospective cohort study of patients ( Results: In the CA and ABI groups, the absence of N20 (36% of CA patients and 41% of ABI patients; specificity = 100%) or N70 (68% of CA patients and 78% of ABI patients) was a strong indicator of poor outcome. Conversely, the presence of N70 was an indicator of a good outcome (AC: specificity = 84.2%, sensitivity = 92.7%; ABI: specificity = 64.2% sensitivity = 91.3%). Conclusion: Somatosensory evoked potentials are useful early prognostic markers with high specificity (N20) and sensitivity (N70). Moreover, N70 has additional potential value for improving the prediction of good long-term functional outcomes. Clinical Trial Registration: [https://clinicaltrials.gov/], identifier [2018/01/001].
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