Evidence map›Paper›PMID 35860188›Full record

ArticleComputational and mathematical methods in medicine2022

Animal Models and Pathogenesis of Ulcerative Colitis.

Xin Gao, Jia Li, Xueping Pang, Kaiyuan Cong, Chunlei Jiang, Bingxuan Han, Jiawei Gao, Zhihao Wang, Jiangshan Hu, Kaijun Wen and 2 more

RetractedOpen access · hybridAbstract readRetracted Publication
In one paragraph

Article in Computational and mathematical methods in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. [Therapeutic mechanism ofNan fang yi ke da xue xue bao = Journal of Southern Medical University · 2024
    Article
  3. Review
  4. Article
  5. Retracted: Animal Models and Pathogenesis of Ulcerative Colitis.Computational and mathematical methods in medicine · 2023
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Xin GaoShandong University of Traditional Chinese Medicine, Shandong, China.
Jia LiShandong University of Traditional Chinese Medicine, Shandong, China.ORCID https://orcid.org/0000-0002-2528-0884
Xueping PangShandong University of Traditional Chinese Medicine, Shandong, China.
Kaiyuan CongShandong University of Traditional Chinese Medicine, Shandong, China.
Chunlei JiangShandong University of Traditional Chinese Medicine, Shandong, China.
Bingxuan HanShandong University of Traditional Chinese Medicine, Shandong, China.
Jiawei GaoShandong University of Traditional Chinese Medicine, Shandong, China.
Zhihao WangShandong University of Traditional Chinese Medicine, Shandong, China.
Jiangshan HuShandong University of Traditional Chinese Medicine, Shandong, China.
Kaijun WenShandong University of Traditional Chinese Medicine, Shandong, China.
Xinfa YeShandong University of Traditional Chinese Medicine, Shandong, China.
Liwen DouShandong University of Traditional Chinese Medicine, Shandong, China.ORCID https://orcid.org/0000-0002-7097-2062
Shandong University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Ulcerative colitis (UC) is a kind of inflammatory bowel disease which is needed to be predicted. Objective: To analyze various animal models of UC conditions and summarizes the animal selection, model progression, and pathogenic mechanisms of UC animal models. Methods: We surveyed the research papers published in PubMed, Google Scholar, Baidu Scholar, CNKI, SciFinder, and Web of Science in the past 5 years and discussed the experimental animals, modeling methods, and pathogenic mechanisms. Results: In the selection of experimental animals, rats are considered the best experimental animals. The mainstream modeling methods can be categorized into the chemical stimulation method, immune stimulation method, and compound method, among which the compound method is the most successful. In the study of the pathogenesis of UC, the pathogenesis of UC is due to various pathogenic factors, such as nitric oxide (NO), prostaglandins (PG), proinflammatory factors (IL, TNF- Conclusion: The method of building an animal model of UC is well-established, providing a more targeted selection of animal models for future related experiments.

Indexed as

Colitis, UlcerativeAnimalsDisease Models, AnimalIntestinal MucosaRatsTumor Necrosis Factor-alphaTumor Necrosis Factor-alpha

Identifiers

PMID35860188
PMCPMC9293489
OpenAlexW4285040026

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.