Evidence map›Paper›PMID 35859862›Full record

ArticleACS medicinal chemistry letters2022

The Ukrainian Factor in Early-Stage Drug Discovery in the Context of Russian Invasion: The Case of Enamine Ltd.

Ivan S Kondratov, Yurii S Moroz, Oleksandr O Grygorenko, Andrey A Tolmachev

Abstract read
In one paragraph

Article in ACS medicinal chemistry letters, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Challenges for chemistry in Ukraine after the war: Ukrainian science requires rebuilding and support.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ivan S KondratovEnamine Ltd (www.enamine.net), Chervonotkatska Street 78, Kyïv 02094, Ukraine.ORCID https://orcid.org/0000-0003-0192-0725
Yurii S MorozChemspace (www.chem-space.com), Chervonotkatska Street 85, Kyïv 02094, Ukraine.
Oleksandr O GrygorenkoEnamine Ltd (www.enamine.net), Chervonotkatska Street 78, Kyïv 02094, Ukraine.ORCID https://orcid.org/0000-0002-6036-5859
Andrey A TolmachevEnamine Ltd (www.enamine.net), Chervonotkatska Street 78, Kyïv 02094, Ukraine.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ukrainian companies occupy an important niche in the global drug discovery process; however, before the Russian invasion, the role of Ukraine was not obvious. The biggest Ukrainian fine chemical supplier, Enamine Ltd, had to stop operation for more than a month, which significantly affected various early-stage drug discovery projects. The role of Enamine in drug discovery and the company's past and future in the context of the Russian invasion are described in this Viewpoint.

Identifiers

PMID35859862
PMCPMC9290057

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.