Evidence map›Paper›PMID 35859797›Full record

ArticleOpen medicine (Warsaw, Poland)2022

Protective effects of glaucocalyxin A on the airway of asthmatic mice.

Si Chen, Ying Piao, Yilan Song, Zhiguang Wang, Jingzhi Jiang, Yihua Piao, Li Li, Chang Xu, Liangchang Li, Yongxue Chi and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Open medicine (Warsaw, Poland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. DGA ameliorates severe acute pancreatitis through modulating macrophage pyroptosis.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2024
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Si ChenDepartment of Pediatrics, Affiliated Hospital of Yanbian University, Yanji 133099, Jilin, P. R. China.
Ying PiaoJilin Key Laboratory for Immune and Targeting Research on Common Allergic Diseases, Yanbian University, Yanji 133000, Jilin, P. R. China.
Yilan SongJilin Key Laboratory for Immune and Targeting Research on Common Allergic Diseases, Yanbian University, Yanji 133000, Jilin, P. R. China.
Zhiguang WangJilin Key Laboratory for Immune and Targeting Research on Common Allergic Diseases, Yanbian University, Yanji 133000, Jilin, P. R. China.
Jingzhi JiangJilin Key Laboratory for Immune and Targeting Research on Common Allergic Diseases, Yanbian University, Yanji 133000, Jilin, P. R. China.
Yihua PiaoJilin Key Laboratory for Immune and Targeting Research on Common Allergic Diseases, Yanbian University, Yanji 133000, Jilin, P. R. China.
Li LiJilin Key Laboratory for Immune and Targeting Research on Common Allergic Diseases, Yanbian University, Yanji 133000, Jilin, P. R. China.
Chang XuJilin Key Laboratory for Immune and Targeting Research on Common Allergic Diseases, Yanbian University, Yanji 133000, Jilin, P. R. China.
Liangchang LiJilin Key Laboratory for Immune and Targeting Research on Common Allergic Diseases, Yanbian University, Yanji 133000, Jilin, P. R. China.
Yongxue ChiDepartment of Pediatrics, Affiliated Hospital of Yanbian University, No. 1327, Juzi Street, Yanji 133099, Jilin, P. R. China.
Guihua JinJilin Key Laboratory for Immune and Targeting Research on Common Allergic Diseases, Yanbian University, Yanji 133000, Jilin, P. R. China.
Guanghai YanDepartment of Neonatology, Children's Hospital of Changchun, Changchun 130061, Jilin, P. R. China.
Yanbian University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study is to investigate the protective effects of glaucocalyxin A (GLA) on airways in mouse models of asthma, concerning the inflammatory mediators, Th1/Th2 subgroup imbalance, and Toll-like receptor 4 (TLR4)/NF-κB signaling pathway. Hematoxylin and eosin/periodic acid-Schiff staining was used to observe the pathological changes in lung tissues. Inflammatory cytokine contents in the bronchoalveolar lavage fluid were detected by enzyme-linked immunosorbent assay. Protein expression levels were detected with Western blot, immunohistochemistry, and immunofluorescence.

Indexed as

airwayasthmaglaucocalyxin Ainflammatory responsesTLR4/NF-κB signaling pathway

Identifiers

PMID35859797
PMCPMC9263894
OpenAlexW4285308751

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.