Evidence map›Paper›PMID 35859628›Full record

ArticleNeuro-ophthalmology (Aeolus Press)2022

Radiological Latency in Pineal Germinoma: A Case Report and Literature Review.

Ivan Chi Hin Siu, Noel Ching Yan Chan, Xian Lun Zhu, Ryan Pak To Yuen, Zhexi He, Danny Tat Ming Chan

Abstract readCase Reports
In one paragraph

Article in Neuro-ophthalmology (Aeolus Press), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ivan Chi Hin SiuDivision of Neurosurgery, Department of Surgery, Prince of Wales Hospital, Chinese University of Hong Kong, Shatin, The Hong Kong Special Administrative Region (HKSAR).
Noel Ching Yan ChanDepartment of Ophthalmology and Visual Sciences, Prince of Wales Hospital, Shatin & Alice Ho Miu King Nethersole Hospital, Tai Pao, The Hong Kong Special Administrative Region (HKSAR).
Xian Lun ZhuDivision of Neurosurgery, Department of Surgery, Prince of Wales Hospital, Chinese University of Hong Kong, Shatin, The Hong Kong Special Administrative Region (HKSAR).
Ryan Pak To YuenDivision of Neurosurgery, Department of Surgery, Prince of Wales Hospital, Chinese University of Hong Kong, Shatin, The Hong Kong Special Administrative Region (HKSAR).
Zhexi HeDivision of Neurosurgery, Department of Surgery, Prince of Wales Hospital, Chinese University of Hong Kong, Shatin, The Hong Kong Special Administrative Region (HKSAR).
Danny Tat Ming ChanDivision of Neurosurgery, Department of Surgery, Prince of Wales Hospital, Chinese University of Hong Kong, Shatin, The Hong Kong Special Administrative Region (HKSAR).

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Suprasellar germinomas can present with non-diagnostic, or even normal results on imaging. The spectrum of reported cases ranges from normal imaging, thickened pituitary stalks, to discrete tumour growths. This similar phenomenon is less commonly seen in the pineal region, or bifocal germinomas, and the literature is sparse with only a few case series or reports mentioning a similar presentation of signs and symptoms preceding radiological evidence of diagnosis. We report a case of pineal germinoma presenting with dorsal midbrain syndrome with no evidence of tumour growth on initial imaging despite symptoms. For patients presenting with this clinical radiological latent period, follow-up imaging is useful to identify interval development of germinomas. This applies to patients with dorsal midbrain syndrome, or even other unexplained ophthalmoplegia, as the initial sign of pineal region germinoma, despite normal imaging.

Indexed as

dorsal midbrain syndromeintracranial germ cell tumoursParinaud syndromePineal germinomaradiological latency

Identifiers

PMID35859628
PMCPMC9291675

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.