Evidence map›Paper›PMID 35859624›Full record

ReviewBeilstein journal of organic chemistry2022

Synthesis of odorants in flow and their applications in perfumery.

Merlin Kleoff, Paul Kiler, Philipp Heretsch

Abstract readReview
In one paragraph

Review in Beilstein journal of organic chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Isocampholenic Acid Derivatives as Potential Fragrances.Molecules (Basel, Switzerland) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Merlin KleoffFreie Universität Berlin, Institut für Chemie und Biochemie, Fabeckstr. 34-36, 14195 Berlin, Germany.ORCID https://orcid.org/0000-0001-7350-542X
Paul KilerPK Perfumes, Menifee, California, United States of America.ORCID https://orcid.org/0000-0002-7316-575X
Philipp HeretschLeibniz Universität Hannover, Institut für Organische Chemie, Schneiderberg 1B, 30167 Hannover, Germany.ORCID https://orcid.org/0000-0002-9967-3541

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Continuous flow technology is a key technology for sustainable manufacturing with numerous applications for the synthesis of fine chemicals. In recent years, the preparation of odorants utilizing the advantages of flow reactors received growing attention. In this review, we give an overview of selected methods for the synthesis of odorants in flow, including heterogeneously catalyzed reactions, gas reactions, and photochemical C-H functionalization processes. After a brief introduction on types of odorants, the presented odorant syntheses are ordered according to the main odor families "fruity", "green", "marine", "floral", "spicy", "woody", "ambery", and "musky" and their use and importance for perfumery is briefly discussed.

Indexed as

flow chemistryfragrancesodorantsscentsterpenes

Identifiers

PMID35859624
PMCPMC9263551

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.