Evidence map›Paper›PMID 35859353›Full record

SynthesisBrain : a journal of neurology2022

Vestibular migraine treatment: a comprehensive practical review.

Duncan Smyth, Zelie Britton, Louisa Murdin, Qadeer Arshad, Diego Kaski

Open access · greenAbstract readMeta-AnalysisReview
In one paragraph

Synthesis in Brain : a journal of neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 8 pooled it
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 8 syntheses or guidelines pooled it, 81 citations in OpenAlex.

  1. The Effectiveness of Vestibular Rehabilitation in Vestibular Migraine: A Systematic Review.Journal of the Association for Research in Otolaryngology : JARO · 2026
    Pooled it
  2. Pooled it
  3. Prophylactic Management of Vestibular Migraine: A Systematic Review.Annals of clinical and translational neurology · 2025
    Pooled it
  4. Pooled it
  5. Pharmacological interventions for prophylaxis of vestibular migraine.The Cochrane database of systematic reviews · 2023
    Pooled it
  6. Pharmacological interventions for acute attacks of vestibular migraine.The Cochrane database of systematic reviews · 2023
    Pooled it
  7. Non-pharmacological interventions for prophylaxis of vestibular migraine.The Cochrane database of systematic reviews · 2023
    Pooled it
  8. Pooled it
  9. Trial
  10. Article
  11. Flunarizine and cinnarizine in the prophylaxis of vestibular migraine and migraine-associated menière's disease: An 8-month retrospective study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
  12. Review
  13. Review
  14. Article
  15. [The SCD diagnostic strategy, procedure and pathway for episodic vestibular syndrome].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2026
    Review
  16. Article
  17. Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Duncan SmythDepartment of Neuro-Otology, National Hospital for Neurology and Neurosurgery, London, UK.
Zelie BrittonDepartment of Neuro-Otology, National Hospital for Neurology and Neurosurgery, London, UK.
Louisa MurdinDepartment of Ear, Nose and Throat, Guy's and St Thomas' NHS Foundation Trust, London, UK.
Qadeer ArshadDepartment of Neuroscience, Psychology and Behaviour, University of Leicester, Leicester, UK.
Diego KaskiDepartment of Neuro-Otology, National Hospital for Neurology and Neurosurgery, London, UK.
National Hospital for Neurology and Neurosurgery · GBUniversity College London · GBUniversity of Leicester · GB

Funding

Department of Health
6 · The paper itself

Abstract

Vestibular migraine is an underdiagnosed but increasingly recognized neurological condition that causes episodic vertigo associated with other features of migraine. It is now thought to be the most common cause of spontaneous (non-positional) episodic vertigo, affecting up to 1% of the population. A meta-analysis of preventative treatments for vestibular migraine was published in 2021, but the authors were unable to establish a preferred treatment strategy due to low quality of evidence and heterogeneity of study design and outcome reporting. Therefore, there remains a clinical need for pragmatic management guidelines specific to vestibular migraine using the available evidence. Here, we provide a practical review utilizing a systematic qualitative assessment of the evidence for abortive and preventative interventions in adults. The overall evidence base for vestibular migraine treatment is of low quality. Nevertheless, we provide practical treatment recommendations based on the available evidence and our experience to help guide clinicians treating patients with vestibular migraine. We also discuss how future clinical trials could be designed to improve the quality of evidence in this condition.

Indexed as

DizzinessMigraine DisordersAdultHumansVertigoclinical trialsoutcomesprophylaxistreatmentvestibular migraine

Identifiers

PMID35859353
PMCPMC9679161
OpenAlexW4286005086

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.