ReviewBiological trace element research2023
Exploration of Whole Blood Chromium as Biomarker of Hexavalent Chromium Exposure: Based on Literature Review and Monte Carlo Simulation.
Review in Biological trace element research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Low-Dose Hexavalent Chromium Exposure Induces Endoplasmic Reticulum Stress-Mediated Apoptosis in Rat Liver.Biological trace element research · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hexavalent chromium (Cr(VI)) is a sort of common industrial poison and environmental pollutant posing great health threat to the population. Appropriate biomarkers are indispensable indicative tools in the biological monitoring and health risk assessment of Cr(VI). In this study, we explored the rationality and feasibility of whole blood Cr serving as the biomarker of internal exposure with corroboration drawn from literature review and Monte Carlo simulation. It was indicated that the whole blood Cr had practical operability in the large-scale population researches and robust biological significance with broad association with various Cr(VI)-related effect indices. The simulated distribution of whole blood Cr concentration in exposed populations was about three times higher than that of the control (13.52 ± 24.99 vs. 4.25 ± 11.37 μg/L, P < 0.05; 6.73 ± 10.92 μg/L vs. 1.96 ± 2.05 μg/L in China, P < 0.05), which suggested a great discriminatory ability that might be supported as evidence for its reasonable application.
Indexed as
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.