Evidence map›Paper›PMID 35859200›Full record

ArticleNature2022

A DNA origami rotary ratchet motor.

Anna-Katharina Pumm, Wouter Engelen, Enzo Kopperger, Jonas Isensee, Matthias Vogt, Viktorija Kozina, Massimo Kube, Maximilian N Honemann, Eva Bertosin, Martin Langecker and 3 more

Abstract read
In one paragraph

Article in Nature, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

71 citing papers in PubMed.

  1. Review
  2. Article
  3. Magnetic DNA Origami Nanorotors.Advanced materials (Deerfield Beach, Fla.) · 2026
    Article
  4. Article
  5. Review
  6. A nanoscale Jitterbug transformer from DNA.Nature communications · 2026
    Article
  7. Article
  8. Article
  9. Assembly-Energetics-Control (AEC) Design Framework for Rotary DNA Nanomachines.Chembiochem : a European journal of chemical biology · 2026
    Review
  10. Review
  11. Programming DNA machines to move.Nature reviews. Chemistry · 2026
    Review
  12. Article
  13. Article
  14. Unraveling the Folding Dynamics of DNA Origami Structures.Small (Weinheim an der Bergstrasse, Germany) · 2025
    Article
  15. Article
  16. Synthesis and Incorporation of a pH-Responsive Nucleoside Into DNA Sequences.Chembiochem : a European journal of chemical biology · 2025
    Article
  17. Interactions Between Active Matters and Endogenous Fields.Advanced materials (Deerfield Beach, Fla.) · 2025
    Review
  18. Article
  19. Measuring multisubunit mechanics of geometrically programmed colloidal assemblies via cryo-EM multi-body refinement.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  20. Article

11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Anna-Katharina PummLehrstuhl für Biomolekulare Nanotechnologie, Physik Department & Munich Institute of Biomedical Engineering, Technische Universität München, Garching near Munich, Germany.ORCID http://orcid.org/0000-0003-1983-194X
Wouter EngelenLehrstuhl für Biomolekulare Nanotechnologie, Physik Department & Munich Institute of Biomedical Engineering, Technische Universität München, Garching near Munich, Germany.ORCID http://orcid.org/0000-0001-8779-9887
Enzo KoppergerLehrstuhl für Physik Synthetischer Biosysteme, Physik Department, Technische Universität München, Garching near Munich, Germany.ORCID http://orcid.org/0000-0002-8602-3259
Jonas IsenseeMax Planck Institute for Dynamics and Self-Organization, Göttingen, Germany.ORCID http://orcid.org/0000-0001-6600-5590
Matthias VogtLehrstuhl für Physik Synthetischer Biosysteme, Physik Department, Technische Universität München, Garching near Munich, Germany.ORCID http://orcid.org/0000-0002-6900-6123
Viktorija KozinaLehrstuhl für Biomolekulare Nanotechnologie, Physik Department & Munich Institute of Biomedical Engineering, Technische Universität München, Garching near Munich, Germany.
Massimo KubeLehrstuhl für Biomolekulare Nanotechnologie, Physik Department & Munich Institute of Biomedical Engineering, Technische Universität München, Garching near Munich, Germany.
Maximilian N HonemannLehrstuhl für Biomolekulare Nanotechnologie, Physik Department & Munich Institute of Biomedical Engineering, Technische Universität München, Garching near Munich, Germany.ORCID http://orcid.org/0000-0001-7805-906X
Eva BertosinLehrstuhl für Biomolekulare Nanotechnologie, Physik Department & Munich Institute of Biomedical Engineering, Technische Universität München, Garching near Munich, Germany.ORCID http://orcid.org/0000-0001-9185-3954
Martin LangeckerLehrstuhl für Physik Synthetischer Biosysteme, Physik Department, Technische Universität München, Garching near Munich, Germany.
Ramin GolestanianMax Planck Institute for Dynamics and Self-Organization, Göttingen, Germany. ramin.golestanian@ds.mpg.de.ORCID http://orcid.org/0000-0002-3149-4002
Friedrich C SimmelLehrstuhl für Physik Synthetischer Biosysteme, Physik Department, Technische Universität München, Garching near Munich, Germany. simmel@tum.de.ORCID http://orcid.org/0000-0003-3829-3446
Hendrik DietzLehrstuhl für Biomolekulare Nanotechnologie, Physik Department & Munich Institute of Biomedical Engineering, Technische Universität München, Garching near Munich, Germany. dietz@tum.de.ORCID http://orcid.org/0000-0003-1270-3662

Funding

European Research Council 724261
6 · The paper itself

Abstract

To impart directionality to the motions of a molecular mechanism, one must overcome the random thermal forces that are ubiquitous on such small scales and in liquid solution at ambient temperature. In equilibrium without energy supply, directional motion cannot be sustained without violating the laws of thermodynamics. Under conditions away from thermodynamic equilibrium, directional motion may be achieved within the framework of Brownian ratchets, which are diffusive mechanisms that have broken inversion symmetry

Indexed as

DNAFacilitated DiffusionMolecular Motor ProteinsHydrogen-Ion ConcentrationMotionMovementOsmolar ConcentrationProton-Translocating ATPasesStochastic ProcessesTemperatureThermodynamicsDNAMolecular Motor ProteinsProton-Translocating ATPases

Identifiers

PMID35859200
PMCPMC9300469

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.