ArticleNature2022
Neurotensin orchestrates valence assignment in the amygdala.
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Article in Nature, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.
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52citing papers in PubMed
7.1field-weighted citation impact, top 2% of its field
What it found
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Who cites it
52 citing papers in PubMed, 86 citations in OpenAlex.
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- Paratenial thalamus engages in reciprocal and broadcast circuits with the prefrontal cortex.Cell reports · 2026Article
- Basolateral amygdala neurons await oscillatory recruitment into valence-relevant ensembles.bioRxiv : the preprint server for biology · 2026Article
- Basolateral amygdala neurons await oscillatory recruitment into valence-relevant ensembles.Research square · 2026Article
- Amygdalostriatal transition zone neurons encode sustained cue responses to guide defensive behaviors.Neuron · 2026Article
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- Convergence and Segregation of Excitatory and Inhibitory Afferents in the Paraventricular Thalamic Nucleus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Direction-selective laterodorsal thalamic nucleus encodes optic flow and turning in spatial navigation.Neuron · 2025Article
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- Dynorphin modulates reward-seeking actions through a pallido-amygdala cholinergic circuit.Neuron · 2025Article
- Article
Corrections and comments
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Authors and funding
34 authors at 13 institutions in 6 countries.
Hao Li *Salk Institute for Biological Studies, La Jolla, CA, USA.
Praneeth Namburi *The Picower Institute for Learning and Memory, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA.
Jacob M Olson *The Picower Institute for Learning and Memory, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA.ORCID http://orcid.org/0000-0001-6351-3274
Matilde BorioSalk Institute for Biological Studies, La Jolla, CA, USA.
Mackenzie E LemieuxSalk Institute for Biological Studies, La Jolla, CA, USA.ORCID http://orcid.org/0000-0001-6015-8668
Anna BeyelerThe Picower Institute for Learning and Memory, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA.ORCID http://orcid.org/0000-0003-2371-5706
Gwendolyn G CalhoonThe Picower Institute for Learning and Memory, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA.
Natsuko Hitora-ImamuraThe Picower Institute for Learning and Memory, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA.
Austin A ColeySalk Institute for Biological Studies, La Jolla, CA, USA.
Avraham LibsterSalk Institute for Biological Studies, La Jolla, CA, USA.
Aneesh BalSalk Institute for Biological Studies, La Jolla, CA, USA.
Xin JinSociety of Fellows, Harvard University, MA, USA.ORCID http://orcid.org/0000-0003-2344-992X
Huan WangState Key Laboratory of Membrane Biology, Peking University School of Life Sciences, Peking-Tsinghua Center for Life Science, IDG/McGovern Institute for Brain Research at PKU, Beijing, China.
Caroline JiaSalk Institute for Biological Studies, La Jolla, CA, USA.
Sourav R ChoudhuryBroad Institute of MIT and Harvard, Cambridge, MA, USA.
Xi ShiBroad Institute of MIT and Harvard, Cambridge, MA, USA.
Ada C Felix-OrtizThe Picower Institute for Learning and Memory, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA.
Verónica de la FuenteThe Picower Institute for Learning and Memory, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA.
Vanessa P BarthThe Picower Institute for Learning and Memory, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA.
Hunter O KingThe Picower Institute for Learning and Memory, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA.
Ehsan M IzadmehrThe Picower Institute for Learning and Memory, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA.
Jasmin S RevannaSalk Institute for Biological Studies, La Jolla, CA, USA.
Kanha BatraSalk Institute for Biological Studies, La Jolla, CA, USA.ORCID http://orcid.org/0000-0001-6401-4274
Kyle B FischerSalk Institute for Biological Studies, La Jolla, CA, USA.
Laurel R KeyesSalk Institute for Biological Studies, La Jolla, CA, USA.
Nancy Padilla-CoreanoSalk Institute for Biological Studies, La Jolla, CA, USA.ORCID http://orcid.org/0000-0001-9293-2697
Cody A SicilianoThe Picower Institute for Learning and Memory, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA.ORCID http://orcid.org/0000-0001-9871-2089
Kenneth M McCulloughDivision of Depression and Anxiety Disorders, McLean Hospital, Belmont, MA, USA.ORCID http://orcid.org/0000-0003-4908-2302
Romy WichmannSalk Institute for Biological Studies, La Jolla, CA, USA.ORCID http://orcid.org/0000-0002-4506-8813
Kerry J ResslerDivision of Depression and Anxiety Disorders, McLean Hospital, Belmont, MA, USA.ORCID http://orcid.org/0000-0002-5158-1103
Ila R FieteMcGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA, USA.ORCID http://orcid.org/0000-0003-4738-2539
Feng ZhangBroad Institute of MIT and Harvard, Cambridge, MA, USA.ORCID http://orcid.org/0000-0003-0178-7995
Yulong LiState Key Laboratory of Membrane Biology, Peking University School of Life Sciences, Peking-Tsinghua Center for Life Science, IDG/McGovern Institute for Brain Research at PKU, Beijing, China.ORCID http://orcid.org/0000-0002-9166-9919
Kay M TyeSalk Institute for Biological Studies, La Jolla, CA, USA. tye@salk.edu.ORCID http://orcid.org/0000-0002-2435-0182
Salk Institute for Biological Studies · USBroad Institute · USMassachusetts Institute of Technology · USHarvard University · USPeking University · CNBates College · USConsejo Nacional de Investigaciones Científicas y Técnicas · ARHokkaido University · JPMcGovern Institute for Brain Research · USTechnical University of Munich · DEUniversité de Bordeaux · FRVanderbilt University · USWhitehead Institute for Biomedical Research · US
Funding
SPARED CenterP50MH115874 · NIMH · MCLEAN HOSPITAL · PI CARLEZON, WILLIAM A. · 2019 to 2023
$13.7MQuantitative Neuroscience: Tools for Bridging Levels of AnalysisT32NS007292 · NINDS · BRANDEIS UNIVERSITY · PI GINA G TURRIGIANO · 1986 to 2026
$12.7MPathways in Biological Sciences Training ProgramT32GM133351 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Matthew Daugherty, Randolph Y. Hampton · 2020 to 2026
$9.9MCell Type Specific Genomic and Functional Dissection of Fear-Off Amygdala PathwaysR01MH108665 · NIMH · MCLEAN HOSPITAL · PI BOLSHAKOV, VADIM, RESSLER, KERRY J. · 2016 to 2025
$7.5MNeural Circuit Mechanisms of Social Homeostasis in Individuals and Supraorganismal Social GroupsDP1AT009925 · NCCIH · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI TYE, KAY MAXINE · 2017 to 2021
$6.4MSolving the Valence Assignment ProblemR37MH102441 · NIMH · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI Kay Maxine Tye · 2021 to 2026
$5.6MA Novel Strategy for Combating Obesity: Reprogramming Neural CircuitsDP2DK102256 · NIDDK · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI TYE, KAY MAXINE · 2013 to 2018
$2.7MDissecting the Neural Circuits Encoding Positive and Negative ValenceR01MH102441 · NIMH · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI TYE, KAY MAXINE · 2014 to 2018
$2.0MStudying how the hippocampal-prefrontal-hypothalamic circuit encodes social dominanceR00MH124435 · NIMH · UNIVERSITY OF FLORIDA · PI PADILLA COREANO, NANCY · 2022 to 2024
$785kDefining the role of cortical circuit dynamics in learning and addictionR00DA045103 · NIDA · VANDERBILT UNIVERSITY · PI SICILIANO, CODY · 2020 to 2022
$764kDefining the role of cortical circuit dynamics in learning and addictionK99DA045103 · NIDA · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI SICILIANO, CODY · 2018 to 2019
$366kDetermining how neurotensin mediates valence processing and compulsive cocaine seekingK99DA055111 · NIDA · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI LI, HAO · 2022 to 2023
$345kNCCIH NIH HHS DP1 AT009925NIDA NIH HHS K99 DA045103NIDA NIH HHS K99 DA055111NIDA NIH HHS R00 DA045103NIDDK NIH HHS DP2 DK102256NIGMS NIH HHS T32 GM133351NIMH NIH HHS F32 MH111216NIMH NIH HHS F32 MH115446NIMH NIH HHS K99 MH124435NIMH NIH HHS P50 MH115874NIMH NIH HHS R00 MH124435NIMH NIH HHS R01 MH102441NIMH NIH HHS R01 MH108665NIMH NIH HHS R37 MH102441NINDS NIH HHS T32 NS007292
Abstract
The ability to associate temporally segregated information and assign positive or negative valence to environmental cues is paramount for survival. Studies have shown that different projections from the basolateral amygdala (BLA) are potentiated following reward or punishment learning
Indexed as
Basolateral Nuclear ComplexLearningNeural PathwaysNeurotensinPunishmentRewardCalciumCuesNeuronal PlasticityOptogeneticsThalamic NucleiCalciumNeurotensin
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.