Evidence map›Paper›PMID 35858706›Full record

Observational studyOpen heart2022

Multispecialty multidisciplinary input into comorbidities along with treatment optimisation in heart failure reduces hospitalisation and clinic attendance.

Hani Essa, Lauren Walker, Kevin Mohee, Chukwuemeka Oguguo, Homeyra Douglas, Matthew Kahn, Archana Rao, Julie Bellieu, Justine Hadcroft, Nick Hartshorne-Evans and 5 more

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Open heart, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 22 citations in OpenAlex.

  1. Cardiovascular-Kidney-Metabolic Syndrome: Models of Care.Reviews in cardiovascular medicine · 2026
    Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Updates in heart failure.Clinical medicine (London, England) · 2023
    Article
  10. Article
  11. Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Hani EssaCardiology, Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK.ORCID 0000-0001-9445-2582
Lauren WalkerPharmacology, Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK.
Kevin MoheeCardiology, Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK.ORCID 0000-0002-7409-7197
Chukwuemeka OguguoCardiology, Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK.
Homeyra DouglasCardiology, Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK.
Matthew KahnLiverpool Centre for Cardiovascular Science, University of Liverpool, Liverpool, UK.
Archana RaoLiverpool Centre for Cardiovascular Science, University of Liverpool, Liverpool, UK.
Julie BellieuPalliative Medicine, Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK.
Justine HadcroftRespiratory Medicine, Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK.
Nick Hartshorne-EvansCEO and Founder, The Pumping Marvellous Foundation (Patient-Led Heart Failure Charity), Preston, UK.
Janet BlissChair, NHS Liverpool Clinical Commissioning Group, Liverpool, UK.
Asangaedem AkpanLiverpool Centre for Cardiovascular Science, University of Liverpool, Liverpool, UK.
Christopher WongLiverpool Centre for Cardiovascular Science, University of Liverpool, Liverpool, UK.
Daniel J CuthbertsonLiverpool Centre for Cardiovascular Science, University of Liverpool, Liverpool, UK.ORCID 0000-0002-6128-0822
Rajiv SankaranarayananCardiology, Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK Rajiv.Sankaranarayanan@liverpoolft.nhs.uk.ORCID 0000-0003-2355-2011
University of Liverpool · GBBristol Clinical Commissioning Group · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsHeart failure (HF) is associated with comorbidities which independently influence treatment response and outcomes. This retrospective observational study (January 2020-June 2021) analysed the impact of monthly HF multispecialty multidisciplinary team (MDT) meetings to address management of HF comorbidities and thereby on provision, cost of care and HF outcomes.

methodsPatients acted as their own controls, with outcomes compared for equal periods (for each patient) pre (HF MDT) versus post-MDT (multispecialty) meeting. The multispecialty MDT comprised HF cardiologists (primary, secondary, tertiary care), HF nurses, nephrologist, endocrinologist, palliative care, chest physician, pharmacist, clinical pharmacologist and geriatrician. Outcome measures were (1) all-cause hospitalisations, (2) outpatient clinic attendances and (3) cost.

results334 patients (mean age 72.5±11 years) were discussed virtually through MDT meetings and follow-up duration was 13.9±4 months. Mean age-adjusted Charlson Comorbidity Index was 7.6±2.1 and Rockwood Frailty Score 5.5±1.6. Multispecialty interventions included optimising diabetes therapy (haemoglobin A1c-HbA1c pre-MDT 68±11 mmol/mol vs post-MDT 61±9 mmol/mol; p<0.001), deprescribing to reduce anticholinergic burden (pre-MDT 1.85±0.4 vs 1.5±0.3 post-MDT; p<0.001), initiation of renin-angiotensin aldosterone system inhibitors in HF with reduced ejection fraction (HFrEF) with advanced chronic kidney disease (9% pre vs 71% post-MDT; p<0.001). Other interventions included potassium binders, treatment of anaemia, falls assessment, management of chest conditions, day-case ascitic, pleural drains and palliative support. Total cost of funding monthly multispecialty meetings was £32 400 and resultant 64 clinic appointments cost £9600. The post-MDT study period was associated with reduction in 481 clinic appointments (cost saving £72150) and reduced all-cause hospitalisations (pre-MDT 1.1±0.4 vs 0.6±0.1 post-MDT; p<0.001), reduction of 1586 hospital bed-days and cost savings of £634 400. Total cost saving to the healthcare system was £664 550.

conclusionHF multispecialty virtual MDT model provides integrated, holistic care across all healthcare tiers for management of HF and associated comorbidities. This approach is associated with reduced clinic attendances and all-cause hospitalisations, leading to significant cost savings.

Indexed as

Heart FailureAgedAged, 80 and overAmbulatory Care FacilitiesComorbidityHospitalizationHumansMiddle AgedStroke VolumeHealth Care Economics and OrganizationsHeart FailureOutcome Assessment, Health CarePharmacologyQuality of Health Care

Identifiers

PMID35858706
PMCPMC9305818
OpenAlexW4286255095

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.