Evidence map›Paper›PMID 35858660›Full record

ReviewAmerican journal of obstetrics & gynecology MFM2022

Assessment of the fetal lungs in utero.

Carla L Avena-Zampieri, Jana Hutter, Mary Rutherford, Anna Milan, Megan Hall, Alexia Egloff, David F A Lloyd, Surabhi Nanda, Anne Greenough, Lisa Story

Open access · hybridAbstract readReview
In one paragraph

Review in American journal of obstetrics & gynecology MFM, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 30 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Carla L Avena-ZampieriDepartment of Women and Children's Health, King's College London, London, United Kingdom; Centre for the Developing Brain, King's College London, London, United Kingdom.
Jana HutterCentre for the Developing Brain, King's College London, London, United Kingdom.
Mary RutherfordCentre for the Developing Brain, King's College London, London, United Kingdom.
Anna MilanNeonatal Unit, Guy's and St Thomas' National Health Service Foundation Trust, London, United Kingdom.
Megan HallDepartment of Women and Children's Health, King's College London, London, United Kingdom; Centre for the Developing Brain, King's College London, London, United Kingdom.
Alexia EgloffCentre for the Developing Brain, King's College London, London, United Kingdom.
David F A LloydCentre for the Developing Brain, King's College London, London, United Kingdom.
Surabhi NandaFetal Medicine Unit, Guy's and St Thomas' National Health Service Foundation Trust, London, United Kingdom.
Anne GreenoughDepartment of Women and Children's Health, King's College London, London, United Kingdom; Neonatal Unit, King's College Hospital, London, United Kingdom; Asthma UK Centre in Allergic Mechanisms of Asthma, King's College London, London, United Kingdom; National Institute for Health and Care Research Biomedical Research Centre, Guy's & St Thomas National Health Service Foundation Trust and King's College London, London, United Kingdom.
Lisa StoryDepartment of Women and Children's Health, King's College London, London, United Kingdom; Centre for the Developing Brain, King's College London, London, United Kingdom; Fetal Medicine Unit, Guy's and St Thomas' National Health Service Foundation Trust, London, United Kingdom. Electronic address: lisa.story@kcl.ac.uk.
King's College London · GBNational Health Service · GB

Funding

Structure and function of the placenta from implantation to delivery: a next generation MRI approachU01HD087202 · NICHD · KING'S COLLEGE LONDON · PI ALEXANDER, DANIEL, ALJABAR, PAUL · 2015 to 2015
$3.2M
Department of HealthMedical Research Council G1000758Medical Research Council MR/T018119/1Medical Research Council MR/W019469/1NICHD NIH HHS U01 HD087202Wellcome Trust 201374/Z/16/ZWellcome Trust WT203148/Z/16/Z
6 · The paper itself

Abstract

Antenatal diagnosis of abnormal pulmonary development has improved significantly over recent years because of progress in imaging techniques. Two-dimensional ultrasound is the mainstay of investigation of pulmonary pathology during pregnancy, providing good prognostication in conditions such as congenital diaphragmatic hernia; however, it is less validated in other high-risk groups such as those with congenital pulmonary airway malformation or preterm premature rupture of membranes. Three-dimensional assessment of lung volume and size is now possible using ultrasound or magnetic resonance imaging; however, the use of these techniques is still limited because of unpredictable fetal motion, and such tools have also been inadequately validated in high-risk populations other than those with congenital diaphragmatic hernia. The advent of advanced, functional magnetic resonance imaging techniques such as diffusion and T2* imaging, and the development of postprocessing pipelines that facilitate motion correction, have enabled not only more accurate evaluation of pulmonary size, but also assessment of tissue microstructure and perfusion. In the future, fetal magnetic resonance imaging may have an increasing role in the prognostication of pulmonary abnormalities and in monitoring current and future antenatal therapies to enhance lung development. This review aims to examine the current imaging methods available for assessment of antenatal lung development and to outline possible future directions.

Indexed as

Hernias, Diaphragmatic, CongenitalLung DiseasesFemaleHumansInfant, NewbornLungLung Volume MeasurementsPregnancyPrenatal Diagnosisfetalmagnetic resonance imagingpulmonary developmentultrasound

Identifiers

PMID35858660
PMCPMC9811184
OpenAlexW4285678393

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.