Evidence map›Paper›PMID 35858647›Full record

ArticleAmerican journal of perinatology2024

Clinical Correlates of Moderate-to-Severe Bronchopulmonary Dysplasia in Preterm Infants following Surgical Necrotizing Enterocolitis.

Parvesh M Garg, Melissa Pippin, Mengna Zhang, Jennifer Ware, Sarah Nelin, Jaslyn Paschal, Neha Varshney, William B Hillegass

Open access · bronzeAbstract read
In one paragraph

Article in American journal of perinatology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Necrotizing enterocolitis.Nature reviews. Disease primers · 2026
    Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Surgical NEC, Randomized Control Trials, Missed Opportunity.Journal of neonatal-perinatal medicine · 2023
    Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Parvesh M GargDepartment of Pediatrics/Neonatology, University of Mississippi Medical Center, Jackson, Mississippi.
Melissa PippinDepartment of Pediatrics/Neonatology, University of Mississippi Medical Center, Jackson, Mississippi.
Mengna ZhangDepartment of Data Science, University of Mississippi Medical Center, Jackson, Mississippi.
Jennifer WareDepartment of Pediatrics/Neonatology, University of Mississippi Medical Center, Jackson, Mississippi.
Sarah NelinDepartment of Pediatrics/Neonatology, University of Mississippi Medical Center, Jackson, Mississippi.
Jaslyn PaschalDepartment of Pediatrics/Neonatology, University of Mississippi Medical Center, Jackson, Mississippi.
Neha VarshneyDepartment of Pathology, University of Mississippi Medical Center, Jackson, Mississippi.
William B HillegassDepartment of Data Science, University of Mississippi Medical Center, Jackson, Mississippi.
University of Mississippi Medical Center · USJackson Memorial Hospital · US

Funding

Tracking and Evaluation CoreU54GM115428 · NIGMS · UNIVERSITY OF MISSISSIPPI MED CTR · PI COMPRETTA, CAROLINE E. · 2016 to 2025
$38.2M
NIGMS NIH HHS U54 GM115428
6 · The paper itself

Abstract

objectiveThe aim of the study is to determine clinical correlates of moderate to severe bronchopulmonary dysplasia (BPD) in preterm infants following surgical necrotizing enterocolitis (NEC). STUDY

designThis is a retrospective, single-center cohort study comparing patients with moderate to severe BPD to patients with non/mild BPD among surgical NEC infants. BPD was defined by NIH 2001 consensus definition.

resultsOf 92 consecutive neonates with surgical NEC, 77% (71/92) had moderate/severe BPD and 22% (21/92) had non/mild BPD. The patent ductus arteriosus (PDA) was significantly higher in those developing moderate/severe BPD (67.6% [48/71]) than non/mild BPD (28.6% [6/21];

conclusionDevelopment of moderate/severe BPD occurred in the majority of preterm infants with surgical NEC in this consecutive series. Preterm infants with moderate/severe BPD were more likely to have a PDA before NEC. Development of moderate/severe BPD was associated with significantly greater burden and duration of postoperative morbidity following surgical NEC. Identifying surgical NEC infants at increased risk of moderate/severe BPD and developing lung protection strategies may improve surgical NEC outcomes. KEY POINTS: · Three-fourths of preterm infants experienced severe lung injury following surgical NEC.. · The infants with severe moderate/severe BPD were most likely associated with greater duration of postoperative morbidity.. · There is need to understand and develop lung protective strategies in infants with surgical NEC..

Indexed as

Bronchopulmonary DysplasiaDuctus Arteriosus, PatentEnterocolitis, NecrotizingInfant, PrematureSeverity of Illness IndexAcute Kidney InjuryFemaleGestational AgeHumansInfant, NewbornLength of StayLogistic ModelsMalePostoperative ComplicationsRespiration, ArtificialRetrospective Studies

Identifiers

PMID35858647
PMCPMC10278056
OpenAlexW4286009301

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.