ArticleCell reports2022
Light regulates xylem cell differentiation via PIF in Arabidopsis.
Article in Cell reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Photoreceptors as central hubs of developmental plasticity and environmental adaptation.Molecules and cells · 2026Review
- A versatile inducible plant model system for dissecting p53 function and discovering novel interaction networks.iScience · 2026Article
- A MYB-Related Transcriptional Module Cooperatively Represses Xylem Development in Poplar.Plant biotechnology journal · 2026Article
- An updated history of TDIF-PXY signalling: a study in cell fate and tissue patterning.The New phytologist · 2025Review
- Spatiotemporal bifurcation of HY5-mediated blue-light signaling regulates wood development during secondary growth.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Near-infrared light and PIF4 promote plant antiviral defense by enhancing RNA interference.Plant communications · 2024Article
- Endogenous and environmental signals in regulating vascular development and secondary growth.Frontiers in plant science · 2024Article
- Time series single-cell transcriptional atlases reveal cell fate differentiation driven by light in Arabidopsis seedlings.Nature plants · 2023Article
- Molecular Mechanisms Underlying the Establishment and Maintenance of Vascular Stem Cells in Arabidopsis thaliana.Plant & cell physiology · 2023Review
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
The balance between cell proliferation and differentiation in the cambium defines the formation of plant vascular tissues. As cambium cells proliferate, subsets of daughter cells differentiate into xylem or phloem. TDIF-PXY/TDR signaling is central to this process. TDIF, encoded by CLE41 and CLE44, activates PXY/TDR receptors to maintain proliferative cambium. Light and water are necessary for photosynthesis; thus, vascular differentiation must occur upon light perception to facilitate the transport of water and minerals to the photosynthetic tissues. However, the molecular mechanism controlling vascular differentiation in response to light remains elusive. In this study we show that the accumulation of PIF transcription factors in the dark promotes TDIF signaling and inhibits vascular cell differentiation. On the contrary, PIF inactivation by light leads to a decay in TDIF activity, which induces vascular cell differentiation. Our study connects light to vascular differentiation and highlights the importance of this crosstalk to fine-tune water transport.
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Registered trials
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