Evidence map›Paper›PMID 35858359›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2022

Spatiotemporal dynamics of calcium signals during neutrophil cluster formation.

Roxana Khazen, Béatrice Corre, Zacarias Garcia, Fabrice Lemaître, Sophie Bachellier-Bassi, Christophe d'Enfert, Philippe Bousso

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Many Cells Make Light Work: Self-Generated Gradients OrganizeCold Spring Harbor perspectives in biology · 2026
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  4. Chemical and Mechanical Regulation of Leukocyte Migration.Cold Spring Harbor perspectives in biology · 2026
    Review
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  11. Necrosis drives susceptibility toInfection and immunity · 2025
    Article
  12. Necrosis drives susceptibility tobioRxiv : the preprint server for biology · 2024
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Roxana KhazenDynamics of Immune Responses Unit, Institut Pasteur, INSERM, Université de Paris Cité, U1223, Paris, France.
Béatrice CorreDynamics of Immune Responses Unit, Institut Pasteur, INSERM, Université de Paris Cité, U1223, Paris, France.
Zacarias GarciaDynamics of Immune Responses Unit, Institut Pasteur, INSERM, Université de Paris Cité, U1223, Paris, France.
Fabrice LemaîtreDynamics of Immune Responses Unit, Institut Pasteur, INSERM, Université de Paris Cité, U1223, Paris, France.
Sophie Bachellier-BassiUnité Biologie et Pathogénicité Fongiques, Institut Pasteur, INRAE, Université de Paris Cité, USC2019, Paris, France.ORCID 0000-0003-3970-4825
Christophe d'EnfertUnité Biologie et Pathogénicité Fongiques, Institut Pasteur, INRAE, Université de Paris Cité, USC2019, Paris, France.ORCID 0000-0002-6235-3886
Philippe BoussoDynamics of Immune Responses Unit, Institut Pasteur, INSERM, Université de Paris Cité, U1223, Paris, France.ORCID 0000-0002-6362-561X
Inserm · FRInstitut Pasteur · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neutrophils form cellular clusters or swarms in response to injury or pathogen intrusion. Yet, intracellular signaling events favoring this coordinated response remain to be fully characterized. Here, we show that calcium signals play a critical role during mouse neutrophil clustering around particles of zymosan, a structural fungal component. Pioneer neutrophils recognizing zymosan or live

Indexed as

CalciumCalcium SignalingLeukotriene B4NeutrophilsAnimalsCandida albicansMiceZymosanCalciumLeukotriene B4Zymosancalciumclusteringimagingneutrophilswarming

Identifiers

PMID35858359
PMCPMC9308126
OpenAlexW4285090189

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.