Evidence map›Paper›PMID 35858345›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2022

Pharmacologic modulation of intracellular Na

Max Lenz, Manuel Salzmann, Cosmin I Ciotu, Christoph Kaun, Konstantin A Krychtiuk, Andreja Rehberger Likozar, Miran Sebestjen, Laura Goederle, Sabine Rauscher, Zoriza Krivaja and 8 more

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 5 institutions in 2 countries.

Max LenzDepartment of Internal Medicine II - Division of Cardiology, Medical University of Vienna, 1090 Vienna, Austria.ORCID 0000-0003-3539-994X
Manuel SalzmannDepartment of Internal Medicine II - Division of Cardiology, Medical University of Vienna, 1090 Vienna, Austria.ORCID 0000-0001-5477-3533
Cosmin I CiotuCenter of Physiology and Pharmacology, Medical University of Vienna, 1090 Vienna, Austria.
Christoph KaunDepartment of Internal Medicine II - Division of Cardiology, Medical University of Vienna, 1090 Vienna, Austria.ORCID 0000-0003-3873-7246
Konstantin A KrychtiukDepartment of Internal Medicine II - Division of Cardiology, Medical University of Vienna, 1090 Vienna, Austria.
Andreja Rehberger LikozarDepartment of Vascular Disease, University Medical Centre Ljubljana, 1000 Ljubljana, Slovenia.ORCID 0000-0002-8592-192X
Miran SebestjenDepartment of Vascular Disease, University Medical Centre Ljubljana, 1000 Ljubljana, Slovenia.ORCID 0000-0001-9907-3522
Laura GoederleDepartment of Laboratory Medicine, Medical University of Vienna, 1090 Vienna, Austria.ORCID 0000-0003-1037-3137
Sabine RauscherCore Facility Imaging, Medical University of Vienna, 1090 Vienna, Austria.
Zoriza KrivajaDepartment of Internal Medicine II - Division of Cardiology, Medical University of Vienna, 1090 Vienna, Austria.ORCID 0000-0003-4587-8856
Christoph J BinderDepartment of Laboratory Medicine, Medical University of Vienna, 1090 Vienna, Austria.
Kurt Huber3rd Medical Department, Cardiology and Intensive Care Medicine, Clinic Ottakring (Wilhelminenhospital), and Sigmund Freud University, Medical Faculty, Vienna, 1020 Austria.
Christian HengstenbergDepartment of Internal Medicine II - Division of Cardiology, Medical University of Vienna, 1090 Vienna, Austria.ORCID 0000-0002-8284-2994
Bruno K PodesserLudwig Boltzmann Institute for Cardiovascular Research, A-1090 Vienna, Austria.ORCID 0000-0002-4641-7202
Michael J M FischerCenter of Physiology and Pharmacology, Medical University of Vienna, 1090 Vienna, Austria.
Johann WojtaDepartment of Internal Medicine II - Division of Cardiology, Medical University of Vienna, 1090 Vienna, Austria.ORCID 0000-0002-1282-9276
Philipp J HohensinnerLudwig Boltzmann Institute for Cardiovascular Research, A-1090 Vienna, Austria.ORCID 0000-0003-4819-3190
Walter S SpeidlDepartment of Internal Medicine II - Division of Cardiology, Medical University of Vienna, 1090 Vienna, Austria.ORCID 0000-0002-7267-3138
Medical University of Vienna · ATLudwig Boltzmann Institute for Cancer Research · ATLjubljana University Medical Centre · SISigmund Freud Privatuniversität Wien · ATUniversity of Ljubljana · SI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Changes in Ca2

Indexed as

Acute Coronary SyndromeCardiovascular AgentsCoronary Artery DiseaseC-Reactive ProteinRanolazineSodiumSodium Channel BlockersAnimalsEndothelial CellsHumansInflammationMiceCardiovascular AgentsC-Reactive ProteinRanolazineSodiumSodium Channel BlockersAtherosclerosisEndotheliumInflammationNF-κBRanolazine

Identifiers

PMID35858345
PMCPMC9303949
OpenAlexW4285086535

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.