Evidence map›Paper›PMID 35858337›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2022

A novel transposable element-mediated mechanism causes antiviral resistance in

Osama Brosh, Daniel K Fabian, Rodrigo Cogni, Ignacio Tolosana, Jonathan P Day, Francesca Olivieri, Manon Merckx, Nazli Akilli, Piotr Szkuta, Francis M Jiggins

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Naturally occurring viruses ofProceedings. Biological sciences · 2024
    Article
  6. Review
  7. Article
  8. Article
  9. Viruses in LaboratoryViruses · 2023
    Article
  10. Article
  11. Article
  12. Article
  13. Transposable elements and xenobiotic resistance.Frontiers in insect science · 2023
    Review
  14. A novel transposable element-mediated mechanism causes antiviral resistance inProceedings of the National Academy of Sciences of the United States of America · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Osama BroshDepartment of Genetics, University of Cambridge, Cambridge, CB2 3EH, United Kingdom.
Daniel K FabianDepartment of Genetics, University of Cambridge, Cambridge, CB2 3EH, United Kingdom.ORCID 0000-0002-9895-2848
Rodrigo CogniDepartment of Genetics, University of Cambridge, Cambridge, CB2 3EH, United Kingdom.
Ignacio TolosanaDepartment of Genetics, University of Cambridge, Cambridge, CB2 3EH, United Kingdom.ORCID 0000-0002-3766-8296
Jonathan P DayDepartment of Genetics, University of Cambridge, Cambridge, CB2 3EH, United Kingdom.
Francesca OlivieriDepartment of Genetics, University of Cambridge, Cambridge, CB2 3EH, United Kingdom.
Manon MerckxDepartment of Genetics, University of Cambridge, Cambridge, CB2 3EH, United Kingdom.ORCID 0000-0002-5019-8241
Nazli AkilliDepartment of Genetics, University of Cambridge, Cambridge, CB2 3EH, United Kingdom.
Piotr SzkutaDepartment of Genetics, University of Cambridge, Cambridge, CB2 3EH, United Kingdom.
Francis M JigginsDepartment of Genetics, University of Cambridge, Cambridge, CB2 3EH, United Kingdom.ORCID 0000-0001-7470-8157
University of Cambridge · GBUniversidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hosts are continually selected to evolve new defenses against an ever-changing array of pathogens. To understand this process, we examined the genetic basis of resistance to the

Indexed as

DicistroviridaeDNA Transposable ElementsDrosophila melanogasterHost-Pathogen InteractionsTudor DomainAnimalsGain of Function MutationSequence DeletionDNA Transposable ElementsadaptationDrosophilatransposable elementTudor domainvirus

Identifiers

PMID35858337
PMCPMC9304006
OpenAlexW4285010561

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.