Evidence map›Paper›PMID 35858332›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2022

Id3 expression identifies CD4

Laura A Shaw, Tianda Z Deng, Kyla D Omilusik, Kennidy K Takehara, Quynh P Nguyen, Ananda W Goldrath

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. ID3 enhances PD-L1 expression by restructuring MYC to promote colorectal cancer immune evasion.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. OCA-B/Pou2af1 is sufficient to promote CD4Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  11. Article
  12. Article
  13. Article
  14. Transcriptional programming of CD4Science immunology · 2023
    Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Laura A ShawDepartment of Biological Sciences, University of California, La Jolla, CA 92093.ORCID 0000-0001-6595-1673
Tianda Z DengDepartment of Biological Sciences, University of California, La Jolla, CA 92093.
Kyla D OmilusikDepartment of Biological Sciences, University of California, La Jolla, CA 92093.
Kennidy K TakeharaDepartment of Biological Sciences, University of California, La Jolla, CA 92093.
Quynh P NguyenDepartment of Biological Sciences, University of California, La Jolla, CA 92093.
Ananda W GoldrathDepartment of Biological Sciences, University of California, La Jolla, CA 92093.
University of California San Diego · US

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM007198 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CHI, NEIL C, INSEL, PAUL A · 1985 to 2024
$29.3M
Transcription factor regulation of CD4 and CD8 T cell effector and memory differentiation and functionP01AI145815 · NIAID · UNIVERSITY OF FLORIDA · PI PIPKIN, MATTHEW EUGENE · 2020 to 2024
$11.0M
TF regulation of CD8 and CD4 T cell memory in both systemic and dermal infectionU19AI109976 · NIAID · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI CROTTY, SHANE P · 2014 to 2018
$10.5M
T cell maintenance: molecular mediators of the TCR-derived survival signalR01AI067545 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GOLDRATH, ANANDA W · 2006 to 2021
$6.1M
Regulation of T cell immunity to viral infectionR01AI072117 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GOLDRATH, ANANDA W · 2008 to 2022
$5.4M
Rheumatic Diseases Research Training GrantT32AR064194 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GARY S FIRESTEIN, Monica Guma · 2013 to 2026
$3.8M
HHS | National Institutes of Health (NIH) 1F31AG043222-01A1HHS | National Institutes of Health (NIH) 5T32AR7534-33HHS | National Institutes of Health (NIH) AR064194HHS | National Institutes of Health (NIH) P01AI145815HHS | National Institutes of Health (NIH) R01AI067545HHS | National Institutes of Health (NIH) U19AI109976NIAID NIH HHS P01 AI145815NIAID NIH HHS R01 AI072117NIAMS NIH HHS T32 AR064194NIGMS NIH HHS T32 GM007198
6 · The paper itself

Abstract

Memory CD4

Indexed as

CD4-Positive T-LymphocytesImmunologic MemoryInhibitor of Differentiation ProteinsTh1 CellsT-Lymphocyte SubsetsAnimalsCell DifferentiationMiceMice, Inbred C57BLIdb3 protein, mouseInhibitor of Differentiation ProteinsCD4memoryT cellTh1

Identifiers

PMID35858332
PMCPMC9303986
OpenAlexW4285014381

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.