ArticleProceedings of the National Academy of Sciences of the United States of America2022
Phenylthiol-BODIPY-based supramolecular metallacycles for synergistic tumor chemo-photodynamic therapy.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Development of a Nucleoside Photosensitizer Efficiently Activated by One- or Two-Photon Absorption in the Optical Therapeutic Window.Journal of the American Chemical Society · 2026Article
- Architecting NIR-II metal supramolecular dyes-illuminating the path to precision medicine.Chemical science · 2026Review
- Recent advances in photodynamic therapy systems based on pillar[n]arene host-guest chemistry.Frontiers in chemistry · 2026Review
- Synthesis of BODIPY-Linked N-Heterocyclic Carbene Metal Complexes for Cancer Chemotheranostics and Catalysis Applications.Chemistry, an Asian journal · 2025Article
- Highly efficient NIR-II photothermal therapy amplified ROS oxide breast tumor therapy by mesoporous gallium-enriched platinum nanomedicine.Materials today. Bio · 2025Article
- Alkyl side-chain engineering enables significant suppression of conformational relaxation for improved near infrared-II imaging-guided uterine recanalization surgery and cancer phototheranostics.Materials today. Bio · 2025Article
- Ru Complex-Functionalized Au Nanospheres for Suppressing Tumor Growth and Metastasis: Photothermal Therapy Combined with Chemotherapy Using Nanoplatforms.International journal of nanomedicine · 2025Article
- A novel nanomedicine integrating ferroptosis and photothermal therapy, well-suitable for PD-L1-mediated immune checkpoint blockade.Materials today. Bio · 2024Review
- Pyrene-acylhydrazone-based Turn-on Fluorescent Probe for Highly Sensitive Detection CuJournal of fluorescence · 2024Article
- Construction of in-situ self-assembled agent for NIR/PET dual-modal imaging and photodynamic therapy for hepatocellular cancer.Journal of nanobiotechnology · 2024Article
- Oxygen-independent organic photosensitizer with ultralow-power NIR photoexcitation for tumor-specific photodynamic therapy.Nature communications · 2024Article
- Photodynamic Therapy: From the Basics to the Current Progress ofMolecules (Basel, Switzerland) · 2023Review
- Terahertz Spectroscopy Sheds Light on Real-Time Exchange Kinetics Occurring through Plasma Membrane during Photodynamic Therapy Treatment.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023Article
- Supramolecular platinum complexes for cancer therapy.Current opinion in chemical biology · 2023Review
- Glycosylated BODIPY- Incorporated Pt(II) Metallacycles for Targeted and Synergistic Chemo-Photodynamic Therapy.Journal of medicinal chemistry · 2023Article
- Reactive oxidative species (ROS)-based nanomedicine for BBB crossing and glioma treatment: current status and future directions.Frontiers in immunology · 2023Review
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The development of more effective tumor therapy remains challenging and has received widespread attention. In the past decade, there has been growing interest in synergistic tumor therapy based on supramolecular coordination complexes. Herein, we describe two triangular metallacycles (1 and 2) constructed by the formation of pyridyl boron dipyrromethene (BODIPY)-platinum coordination. Metallacycle 2 had considerable tumor penetration, as evidenced by the phenylthiol-BODIPY ligand imparting red fluorescent emission at ∼660 nm, enabling bioimaging, and transport visualization within the tumor. Based on the therapeutic efficacy of the platinum(II) acceptor and high singlet oxygen (
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