Evidence map›Paper›PMID 35858299›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2022

The Hippo pathway regulates axis formation and morphogenesis in

Maria Brooun, Willi Salvenmoser, Catherine Dana, Marius Sudol, Robert Steele, Bert Hobmayer, Helen McNeill

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Review
  3. An expanded view of cell competition.Development (Cambridge, England) · 2024
    Review
  4. Review
  5. Article
  6. Deciphering the functional specialization of whole-brain spatiomolecular gradients in the adult brain.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  7. A PAK family kinase and the Hippo/Yorkie pathway modulate WNT signaling to functionally integrate body axes during regeneration.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  8. Review
  9. The Hippo pathway regulates axis formation and morphogenesis inProceedings of the National Academy of Sciences of the United States of America · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 3 countries.

Maria BroounLunenfeld-Tanenbaum Research Institute, Toronto, ON, M5G 1X5, Canada.
Willi SalvenmoserDepartment of Zoology, Center for Molecular Biosciences Innsbruck, University of Innsbruck, A-6020 Innsbruck, Austria.
Catherine DanaDepartment of Biological Chemistry, School of Medicine, University of California, Irvine, CA 92697-1700.
Marius SudolDepartment of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029.
Robert SteeleDepartment of Biological Chemistry, School of Medicine, University of California, Irvine, CA 92697-1700.ORCID 0000-0001-5355-1656
Bert HobmayerDepartment of Zoology, Center for Molecular Biosciences Innsbruck, University of Innsbruck, A-6020 Innsbruck, Austria.ORCID 0000-0002-3401-3294
Helen McNeillDepartment of Developmental Biology, Washington University School of Medicine, St. Louis, MO 63110-1093.
Universität Innsbruck · ATUniversity of California, Irvine · USIcahn School of Medicine at Mount Sinai · USLunenfeld-Tanenbaum Research Institute · CAWashington University in St. Louis · US

Funding

Tools for genetic and genomic studies in HydraR24GM080537 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI STEELE, ROBERT · 2008 to 2011
$1.2M
HHS | NIH | National Institute of General Medical Sciences (NIGMS) 1R24GM080537-01A1NIGMS NIH HHS R24 GM080537
6 · The paper itself

Abstract

How did cells of early metazoan organisms first organize themselves to form a body axis? The canonical Wnt pathway has been shown to be sufficient for induction of axis in Cnidaria, a sister group to Bilateria, and is important in bilaterian axis formation. Here, we provide experimental evidence that in cnidarian

Indexed as

Hippo Signaling PathwayHydraMorphogenesisAnimalsBody PatterningTranscription, GeneticYAP-Signaling ProteinsYAP-Signaling Proteinsaxis formationHippoHydraWntYap

Identifiers

PMID35858299
PMCPMC9304002
OpenAlexW4285093861

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.