Evidence map›Paper›PMID 35857972›Full record

ArticleOpen biology2022

Complex regulatory role of DNA methylation in caste- and age-specific expression of a termite.

Mark C Harrison, Elias Dohmen, Simon George, David Sillam-Dussès, Sarah Séité, Mireille Vasseur-Cognet

Open access · goldAbstract read
In one paragraph

Article in Open biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

  1. Genome Evolution in Social Insects.Genome biology and evolution · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Transgenerational epigenetic effect of kings' aging on offspring's caste fate mediated by sperm DNA methylation in termites.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Mark C HarrisonInstitute for Evolution and Biodiversity, University of Münster, Münster, Germany.ORCID 0000-0003-3095-019X
Elias DohmenInstitute for Evolution and Biodiversity, University of Münster, Münster, Germany.ORCID 0000-0002-7203-2314
Simon GeorgeBiocampus, CNRS, INSERM, Montpellier, France.
David Sillam-DussèsUniversity Sorbonne Paris Nord, Laboratory of Experimental and Comparative Ethology (LEEC), UR4443, Villetaneuse, France.ORCID 0000-0001-5027-8703
Sarah SéitéUMR IRD 242, UPEC, CNRS 7618, UPMC 113, INRAE 1392, Institute of Ecology and Environmental Sciences of Paris, Paris 7 113, Bondy, France.
Mireille Vasseur-CognetUMR IRD 242, UPEC, CNRS 7618, UPMC 113, INRAE 1392, Institute of Ecology and Environmental Sciences of Paris, Paris 7 113, Bondy, France.ORCID 0000-0001-6963-4114
Centre National de la Recherche Scientifique · FRUniversity of Münster · DEUniversité Sorbonne Paris Nord · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The reproductive castes of eusocial insects are often characterized by extreme lifespans and reproductive output, indicating an absence of the fecundity/longevity trade-off. The role of DNA methylation in the regulation of caste- and age-specific gene expression in eusocial insects is controversial. While some studies find a clear link to caste formation in honeybees and ants, others find no correlation when replication is increased across independent colonies. Although recent studies have identified transcription patterns involved in the maintenance of high reproduction throughout the long lives of queens, the role of DNA methylation in the regulation of these genes is unknown. We carried out a comparative analysis of DNA methylation in the regulation of caste-specific transcription and its importance for the regulation of fertility and longevity in queens of the higher termite

Indexed as

AntsIsopteraAge FactorsAnimalsBeesDNA MethylationInsectaageingalternative splicingcaste-biased expressionDNA methylationfertilitytermites

Identifiers

PMID35857972
PMCPMC9256085
OpenAlexW4284708171

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.