ArticleArquivos brasileiros de cardiologia2022
Association between Atrioventricular Block and Mortality in Primary Care Patients: The CODE Study.
Article in Arquivos brasileiros de cardiologia, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Prognostic Value of Inflammatory and Nutritional Indices in Patients Undergoing Permanent Pacemaker Implantation for Degenerative Complete Atrioventricular Block.Medicina (Kaunas, Lithuania) · 2026Article
- CODE-II: a large-scale dataset for artificial intelligence in ECG analysis.NPJ digital medicine · 2026Article
- Nationwide trends and disparities in deaths from second- or third-degree atrioventricular block (1999-2022): A 24-year retrospective analysis of CDC WONDER data.American heart journal plus : cardiology research and practice · 2026Article
- Tele-Electrocardiography and Mortality: Clinical Outcomes in Digital Electrocardiography Cohort-Data from Belo Horizonte, Brazil (CODE-BH).Global heart · 2026Article
- Association between epigenetic aging and atrioventricular block: a two-sample Mendelian randomization study.Epigenomics · 2025Article
- 2025 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Association.Circulation · 2025Review
- Upscaling a regional telecardiology service to a nationwide coverage and beyond: the experience of the Telehealth Network of Minas Gerais.BMJ global health · 2025Article
- His-Ventricular Interval and Incident Pacemaker Implant in Over 3000 Ambulatory Patients Undergoing Invasive Electrophysiologic Procedures.Circulation. Arrhythmia and electrophysiology · 2024Article
- 2024 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Association.Circulation · 2024Review
- First-Degree Atrioventricular Block: A Finding Not Always Benign!Arquivos brasileiros de cardiologia · 2022Article
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9 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundAtrioventricular block (AVB) describes an impairment of conduction from the atria to the ventricles. Although the clinical course of AVB has been evaluated, the findings are from high-income countries and, therefore, cannot be extrapolated to the Latinx population.
objectiveEvaluate the association between AVB and mortality.
methodsPatients from the CODE (Clinical Outcomes in Digital Electrocardiology) study, older than 16 years who underwent digital electrocardiogram (ECG) from 2010 to 2017 were included. ECGs were reported by cardiologists and by automated software. To assess the relationship between AVB and mortality, the log-normal model and the Kaplan-Meier curves were used with two-tailed p-values < 0.05 considered statistically significant.
resultsThe study included 1,557,901 patients; 40.2% were men, and mean age was 51.7 (standard deviation ± 17.6) years. In a mean follow-up of 3.7 years, the mortality rate was 3.35%. The AVB prevalence was 1.38% (21,538). Patients with first-, second-, and third-degree AVB were associated with 24% (relative survival rate [RS] = 0.76; 95% confidence interval [CI]: 0.71-0.81; p < 0.001), 55% (RS = 0.45; 95% CI: 0.27-0.77; p = 0.01), and 64% (RS = 0.36; 95% CI: 0.26-0.49; p < 0.001) lower survival rate when compared to the control group, respectively. Patients with 2:1 AVB had 79% (RS = 0.21; 95% CI: 0.08-0.52; p = 0.005) lower survival rate than the control group. Only Mobitz type I was not associated with higher mortality (p = 0.27).
conclusionAVB was an independent risk factor for overall mortality, with the exception of Mobitz type I.
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