Evidence map›Paper›PMID 35857876›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2022

Genomic and epigenetic landscapes drive CRISPR-based genome editing in

Meichen Pan, Wesley Morovic, Claudio Hidalgo-Cantabrana, Avery Roberts, Kimberly K O Walden, Yong Jun Goh, Rodolphe Barrangou

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 51 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Metabolic Engineering of ProbioticFoods (Basel, Switzerland) · 2026
    Article
  6. Review
  7. Enhanced editing ofApplied and environmental microbiology · 2026
    Article
  8. Occurrence and applications of CRISPR-Cas systems in bifidobacteria.Applied and environmental microbiology · 2026
    Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Review
  16. Highly efficient CRISPR-Cas9 base editing inApplied and environmental microbiology · 2025
    Article
  17. Precision engineering of the probioticApplied and environmental microbiology · 2025
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Meichen PanDepartment of Food, Bioprocessing and Nutrition Sciences, North Carolina State University, Raleigh, NC 27695.
Wesley MorovicIFF Health & Biosciences, International Flavors and Fragrances, Inc., Madison, WI 53716.
Claudio Hidalgo-CantabranaDepartment of Food, Bioprocessing and Nutrition Sciences, North Carolina State University, Raleigh, NC 27695.ORCID 0000-0002-7248-4564
Avery RobertsDepartment of Food, Bioprocessing and Nutrition Sciences, North Carolina State University, Raleigh, NC 27695.
Kimberly K O WaldenRoy J. Carver Biotechnology Center, University of Illinois Urbana-Champaign, Urbana, IL 61801.
Yong Jun GohDepartment of Food, Bioprocessing and Nutrition Sciences, North Carolina State University, Raleigh, NC 27695.ORCID 0000-0001-7998-8469
Rodolphe BarrangouDepartment of Food, Bioprocessing and Nutrition Sciences, North Carolina State University, Raleigh, NC 27695.ORCID 0000-0002-0648-3504
North Carolina State University · USInternational Flavors & Fragrances (United States) · USUniversity of Illinois Urbana-Champaign · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

BifidobacteriumCRISPR-Cas SystemsGene EditingProbioticsGenome, BacterialGenomicsHumansbifidobacteriumCRISPR-Casepigenomicsgenomicsprobiotics

Identifiers

PMID35857876
PMCPMC9335239
OpenAlexW4286008871

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.