ArticleScience advances2022
Dissecting motor skill acquisition: Spatial coordinates take precedence.
Article in Science advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed.
- Trial
- Oculomotor Dance Task: Implications for Audio-Visual-Cued Spatial Learning.Vision (Basel, Switzerland) · 2026Article
- Neurocomputational Mechanisms of Sense of Agency: Literature Review for Integrating Predictive Coding and Adaptive Control in Human-Machine Interfaces.Brain sciences · 2025Review
- Article
- Native learning ability and not age determines the effects of brain stimulation.NPJ science of learning · 2024Article
- Noninvasive modulation of the hippocampal-entorhinal complex during spatial navigation in humans.Science advances · 2024Article
- Article
- Non-invasive deep brain stimulation: interventional targeting of deep brain areas in neurological disorders.Nature reviews. Neurology · 2024Article
- Implication of regional selectivity of dopamine deficits in impaired suppressing of involuntary movements in Parkinson's disease.Neuroscience and biobehavioral reviews · 2024Review
- Multi-focal Stimulation of the Cortico-cerebellar Loop During the Acquisition of a Novel Hand Motor Skill in Chronic Stroke Survivors.Cerebellum (London, England) · 2024Article
- High-intensity acute exercise impacts motor learning in healthy older adults.NPJ science of learning · 2024Article
- Noninvasive theta-burst stimulation of the human striatum enhances striatal activity and motor skill learning.Nature neuroscience · 2023Article
- Early motor skill acquisition in healthy older adults: brain correlates of the learning process.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Practicing a previously unknown motor sequence often leads to the consolidation of motor chunks, which enable its accurate execution at increasing speeds. Recent imaging studies suggest the function of these structures to be more related to the encoding, storage, and retrieval of sequences rather than their sole execution. We found that optimal motor skill acquisition prioritizes the storage of the spatial features of the sequence in memory over its rapid execution early in training, as proposed by Hikosaka in 1999. This process, seemingly diminished in older adults, was partially restored by anodal transcranial direct current stimulation over the motor cortex, as shown by a sharp improvement in accuracy and an earlier yet gradual emergence of motor chunks. These results suggest that the emergence of motor chunks is preceded by the storage of the sequence in memory but is not its direct consequence; rather, these structures depend on, and result from, motor practice.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.