Evidence map›Paper›PMID 35857833›Full record

ArticleScience advances2022

Multiepitope supramolecular peptide nanofibers eliciting coordinated humoral and cellular antitumor immune responses.

Yaoying Wu, Hanning Wen, Zachary J Bernstein, Kelly M Hainline, Tykia S Blakney, Kendra L Congdon, David J Snyder, John H Sampson, Luis Sanchez-Perez, Joel H Collier

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Substituent-Based Modulation of Self-Assembly and Immunogenicity of Amphipathic Peptides.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Review
  12. Peptide Hydrogels and Nanostructures Controlling Biological Machinery.Langmuir : the ACS journal of surfaces and colloids · 2023
    Review
  13. Self-assembling peptides as immunomodulatory biomaterials.Frontiers in bioengineering and biotechnology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Yaoying WuDepartment of Biomedical Engineering, Duke University, Durham, NC, USA.ORCID 0000-0003-0570-2493
Hanning WenDepartment of Biomedical Engineering, Duke University, Durham, NC, USA.
Zachary J BernsteinDepartment of Biomedical Engineering, Duke University, Durham, NC, USA.ORCID 0000-0002-0388-8872
Kelly M HainlineDepartment of Biomedical Engineering, Duke University, Durham, NC, USA.ORCID 0000-0002-0284-6806
Tykia S BlakneyDepartment of Biomedical Engineering, Duke University, Durham, NC, USA.
Kendra L CongdonDepartment of Neurosurgery, Duke University, Durham, NC, USA.ORCID 0000-0003-0571-7927
David J SnyderDepartment of Neurosurgery, Duke University, Durham, NC, USA.
John H SampsonDepartment of Neurosurgery, Duke University, Durham, NC, USA.ORCID 0000-0002-0104-7658
Luis Sanchez-PerezDepartment of Neurosurgery, Duke University, Durham, NC, USA.
Joel H CollierDepartment of Biomedical Engineering, Duke University, Durham, NC, USA.ORCID 0000-0003-3536-4827
Duke University · US

Funding

University Training Program in Biomolecular & Tissue EngineeringT32GM008555 · NIGMS · DUKE UNIVERSITY · PI GERSBACH, CHARLES A. · 1994 to 2021
$8.1M
Modular Self-Assembled Coatings for BiomaterialsR01EB009701 · NIBIB · UNIVERSITY OF CHICAGO · PI COLLIER, JOEL H · 2009 to 2021
$4.3M
University Training Program in Biomolecular and Tissue EngineeringT32GM144291 · NIGMS · DUKE UNIVERSITY · PI Charles A. Gersbach, Tatiana Segura · 2022 to 2026
$2.6M
NIBIB NIH HHS R01 EB009701NIGMS NIH HHS T32 GM008555NIGMS NIH HHS T32 GM144291
6 · The paper itself

Abstract

Subunit vaccines inducing antibodies against tumor-specific antigens have yet to be clinically successful. Here, we use a supramolecular α-helical peptide nanofiber approach to design epitope-specific vaccines raising simultaneous B cell, CD8

Indexed as

Cancer VaccinesMelanomaNanofibersAnimalsEpitopesImmunity, CellularMicePeptidesCancer VaccinesEpitopesPeptides

Identifiers

PMID35857833
PMCPMC9299545
OpenAlexW4285987605

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.