Evidence map›Paper›PMID 35857681›Full record

ArticleWMJ : official publication of the State Medical Society of Wisconsin2022

Treatment Inequity: Examining the Influence of Non-Hispanic Black Race and Ethnicity on Pancreatic Cancer Care and Survival in Wisconsin.

Andrea M Schiefelbein, John K Krebsbach, Amy K Taylor, Jienian Zhang, Chloe E Haimson, Amy Trentham-Dietz, Melissa C Skala, John M Eason, Sharon M Weber, Patrick R Varley and 2 more

Open access · greenAbstract read
In one paragraph

Article in WMJ : official publication of the State Medical Society of Wisconsin, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Unraveling Racial Disparities in Supportive Care Medication Use among End-of-Life Pancreatic Cancer Patients: Focus on Pain Management and Psychiatric Therapies.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2023
    Observational
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Andrea M SchiefelbeinMorgridge Institute for Research, Madison, Wisconsin.
John K KrebsbachUniversity of Wisconsin Carbone Cancer Center, Madison, Wisconsin.
Amy K TaylorDepartment of Medicine, University of Wisconsin School of Medicine and Public Health, Madison Wisconsin.
Jienian ZhangDepartment of Sociology, University of Wisconsin-Madison, Madison, Wisconsin.
Chloe E HaimsonDepartment of Sociology, University of Wisconsin-Madison, Madison, Wisconsin.
Amy Trentham-DietzUniversity of Wisconsin Carbone Cancer Center, Madison, Wisconsin.
Melissa C SkalaMorgridge Institute for Research, Madison, Wisconsin.
John M EasonDepartment of Sociology, University of Wisconsin-Madison, Madison, Wisconsin.
Sharon M WeberUniversity of Wisconsin Carbone Cancer Center, Madison, Wisconsin.
Patrick R VarleyUniversity of Wisconsin Carbone Cancer Center, Madison, Wisconsin.
Syed N ZafarUniversity of Wisconsin Carbone Cancer Center, Madison, Wisconsin.
Noelle K LoConteDepartment of Medicine, University of Wisconsin School of Medicine and Public Health, Madison Wisconsin, ns3@medicine.wisc.edu.
University of Wisconsin Carbone Cancer Center · USUniversity of Wisconsin–Madison · USMorgridge Institute for Research · US

Funding

UW COMPREHENSIVE CANCER CENTER SUPPORTP30CA014520 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI AMY TRENTHAM-DIETZ · 1985 to 2026
$142.6M
Optical imaging of pancreas cancer organoids for drug development and personalized treatmentR01CA211082 · NCI · MORGRIDGE INSTITUTE FOR RESEARCH, INC. · PI SKALA, MELISSA CAROLINE · 2017 to 2021
$3.5M
NCI NIH HHS P30 CA014520NCI NIH HHS R01 CA211082
6 · The paper itself

Abstract

introductionWe investigated race and ethnicity-based disparities in first course treatment and overall survival among Wisconsin pancreatic cancer patients.

methodsWe identified adults diagnosed with pancreatic adenocarcinoma in the Wisconsin Cancer Reporting System from 2004 through 2017. We assessed race and ethnicity-based disparities in first course of treatment via adjusted logistic regression and overall survival via 4 incremental Cox proportional hazards regression models.

resultsThe study included 8,490 patients: 91.3% (n = 7,755) non-Hispanic White; 5.1% (n = 437) non-Hispanic Black, 1.8% (n = 151) Hispanic, 0.6% Native American (n = 53), and 0.6% Asian (n = 51) race and ethnicities. Non-Hispanic Black patients had lower odds of treatment than non-Hispanic White patients for full patient (OR, 0.52; 95% CI, 0.41-0.65) and Medicare cohorts (OR, 0.40; 95% CI, 0.29-0.55). Non-Hispanic Black patients had lower odds of receiving surgery than non-Hispanic White patients (full cohort OR, 0.67 [95% CI, 0.48-0.92]; Medicare cohort OR, 0.57 [95% CI, 0.34-0.93]). Non-Hispanic Black patients experienced worse survival than non-Hispanic White patients in the first 2 incremental Cox proportional hazard regression models (model II HR, 1.18; 95% CI, 1.06-1.31). After adding insurance and treatment course, non-Hispanic Black and non-Hispanic White patients experienced similar survival (HR, 0.98; 95% CI, 0.88-1.09).

conclusionNon-Hispanic Black patients were almost 50% less likely to receive any treatment and 33% less likely to receive surgery than non-Hispanic White patients. After including treatment course, non-Hispanic Black and non-Hispanic White patient survival was similar. Increasing non-Hispanic Black patient treatment rates by addressing structural factors affecting treatment availability and employing culturally humble approaches to treatment discussions may mitigate these disparities.

Indexed as

AdenocarcinomaBlack PeopleHealthcare DisparitiesPancreatic NeoplasmsAdultAgedBlack or African AmericanEthnicityHumansMedicareUnited StatesWhite PeopleWisconsin

Identifiers

PMID35857681
PMCPMC9354557
OpenAlexW4286269595

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.