Evidence map›Paper›PMID 35857105›Full record

ArticleInternational journal of colorectal disease2022

Ovarian metastases in young women with colorectal cancer: a retrospective multicenter cohort study.

R van der Meer, C Bakkers, J A Wegdam, T Lettinga, E G Boerma, F Aarts, I H J T de Hingh, R M H Roumen

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in International journal of colorectal disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

R van der MeerDepartment of Surgery, Máxima Medical Center, P.O. Box 7777, 5500 MB, Veldhoven, The Netherlands. romic.resurge@mmc.nl.
C BakkersDepartment of Surgery, Catharina Cancer Institute, Eindhoven, The Netherlands.
J A WegdamDepartment of Surgery, Elkerliek Hospital, Helmond, The Netherlands.
T LettingaDepartment of Surgery, Sint Jans Gasthuis, Weert, The Netherlands.
E G BoermaDepartment of Surgery, Zuyderland Hospital, Geleen, The Netherlands.
F AartsDepartment of Surgery, VieCuri Medical Center, Venlo, The Netherlands.
I H J T de HinghDepartment of Surgery, Catharina Cancer Institute, Eindhoven, The Netherlands.
R M H RoumenDepartment of Surgery, Máxima Medical Center, P.O. Box 7777, 5500 MB, Veldhoven, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposePrevious studies indicated that approximately 3.4% of female colorectal cancer (CRC) patients are at increased risk of developing ovarian metastases (OM). It has been suggested that young women more frequently develop this form of metastatic disease.

methodsThis study evaluated, in 6 Dutch hospitals, the proportion of young women with CRC who developed OM.

resultsIn a cohort of 200 young (age ≤ 55) women with CRC, the proportion of patients diagnosed with synchronous or metachronous OM was calculated. This study revealed that 5% (n = 10) of young female CRC patients developed ovarian metastases resulting in a 5-year overall survival rate of approximately 40%. Furthermore, six patients had concurrent peritoneal metastases, five patients had bilateral ovarian metastases, and five patients had synchronous metastases, while the median time of the occurrence of metachronous metastases (n = 5) was 19 months.

conclusionThis retrospective multicenter cohort study indicates that 5% of young women with CRC either present with or develop OM. This result appears to be clinically relevant and demonstrates the need for improved surveillance for young women diagnosed with CRC.

Indexed as

Colorectal NeoplasmsCohort StudiesFemaleHumansPrognosisRetrospective StudiesSurvival RateColorectal cancerOvarian metastasesYoung women

Identifiers

PMID35857105

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