Evidence map›Paper›PMID 35857067›Full record

ArticleEuropean journal of trauma and emergency surgery : official publication of the European Trauma Society2023

Associations between elevated high-sensitive cardiac troponin t and outcomes in patients with acute abdominal pain.

Triinu Keskpaik, Peep Talving, Ülle Kirsimägi, Vladislav Mihnovitš, Anni Ruul, Toomas Marandi, Joel Starkopf

Abstract read
PubMed Publisher
In one paragraph

Article in European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Triinu KeskpaikDepartment of Anesthesiology and Intensive Care, Tartu University Hospital, Tartu, Estonia. triinu.keskpaik@kliinikum.ee.
Peep TalvingDepartment of Surgery, Institute of Clinical Medicine, University of Tartu, Tartu, Estonia.
Ülle KirsimägiDepartment of Surgery, Tartu University Hospital, Tartu, Estonia.
Vladislav MihnovitšDepartment of Anesthesiology and Intensive Care, Tartu University Hospital, Tartu, Estonia.
Anni RuulDepartment of Anesthesiology and Intensive Care, Tartu University Hospital, Tartu, Estonia.
Toomas MarandiDepartment of Cardiology, Institute of Clinical Medicine, University of Tartu, Tartu, Estonia.
Joel StarkopfDepartment of Anesthesiology and Intensive Care, Tartu University Hospital, Tartu, Estonia.
Tartu University Hospital · EENorth Estonia Medical Centre · EEUniversity of Tartu · EE

Funding

Eesti Teadusagentuur PRG435
6 · The paper itself

Abstract

purposeThe purpose of this study was to determine outcomes in patients presenting to emergency department (ED) with acute abdominal pain and suspected occult myocardial injury [OMI (high-sensitive cardiac troponin T, hs-cTnT level > 14 ng/L)] without clinical signs of myocardial ischaemia. We hypothesized that OMI is a common entity associated with poor outcomes.

methodsAfter institutional research ethics committee approval, a retrospective review was performed on patients subjected to extended use of hs-cTnT measurements during two months period in patients admitted to ED with a chief complaint of abdominal pain, aged 30 years or older and triaged to red, orange, or yellow categories. Primary outcomes were 30-day, six-month, and one-year mortality, respectively. Adjusted mortality rates were compared using the Cox proportional hazard regression model.

resultsOverall, 1000 consecutive patients were screened. A total of 375 patients were subjected to hs-cTnT measurement and 156 of them (41.6%) experienced OMI. None of the patients had acute myocardial infarction diagnosed in the ED. Patients with OMI had a significantly higher 30-day, six-month and one-year mortality compared to the normal hs-cTnT level group [12.8% (20/156) vs. 3.7% (8/219), p = 0.001, 34.0% (53/156) vs. 6.9% (15/219), p < 0.001 and 39.1% (61/156) vs. 9.1 (20/219), p < 0.001, respectively]. OMI was an independent risk factor for mortality at every time point analyzed.

conclusionOur investigation noted OMI in older patients with co-morbidities and in higher triage category presenting with abdominal pain to ED, respectively. OMI is an independent risk factor for poor outcomes that warrants appropriate screening and management strategy. Our results support the use of hs-cTnT as a prognostication tool in this subgroup of ED patients.

Indexed as

Abdomen, AcuteMyocardial InfarctionAbdominal PainAgedBiomarkersEmergency Service, HospitalHumansRetrospective StudiesTroponin TBiomarkersTroponin TAcute abdominal painCardiac troponinEmergency departmentOccult myocardial injuryPredictive value of tests

Identifiers

PMID35857067
OpenAlexW4285999809

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.