Evidence map›Paper›PMID 35856887›Full record

ArticleMolecular carcinogenesis2022

Gender-based effect of absence of gut microbiota on the protective efficacy of Bifidobacterium longum-fermented rice bran diet against inflammation-associated colon tumorigenesis.

Robin Kumar, Akhilendra K Maurya, Kristopher D Parker, Rama Kant, Hend Ibrahim, Md Imtiazul Kabir, Dileep Kumar, Annika M Weber, Rajesh Agarwal, Kristine A Kuhn and 2 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular carcinogenesis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Fibres and Colorectal Cancer: Clinical and Molecular Evidence.International journal of molecular sciences · 2023
    Review
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 2 countries.

Robin KumarDepartment of Pharmaceutical Sciences, South Dakota State University, Brookings, South Dakota, USA.
Akhilendra K MauryaDepartment of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado-Anschutz Medical Campus, Aurora, Colorado, USA.
Kristopher D ParkerDepartment of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, Colorado, USA.
Rama KantDepartment of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado-Anschutz Medical Campus, Aurora, Colorado, USA.
Hend IbrahimDepartment of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, Colorado, USA.
Md Imtiazul KabirDepartment of Pharmaceutical Sciences, South Dakota State University, Brookings, South Dakota, USA.
Dileep KumarDepartment of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado-Anschutz Medical Campus, Aurora, Colorado, USA.
Annika M WeberDepartment of Food Science and Human Nutrition, Colorado State University, Fort Collins, Colorado, USA.
Rajesh AgarwalDepartment of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado-Anschutz Medical Campus, Aurora, Colorado, USA.ORCID 0000-0002-9455-0235
Kristine A KuhnDivision of Rheumatology, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, Colorado, USA.
Elizabeth P RyanDepartment of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, Colorado, USA.
Komal RainaDepartment of Pharmaceutical Sciences, South Dakota State University, Brookings, South Dakota, USA.ORCID 0000-0003-0371-1070
University of Colorado Anschutz Medical Campus · USSouth Dakota State University · USColorado State University · USGeorgia State University · USZagazig University · EG

Funding

PILOT STUDY--SUBSTRATE METABOLISM IN EXTREMELY LOW BIRTH WEIGHT INFANTSP30DK048520 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI Edward L Melanson · 1995 to 2026
$32.6M
Rice Bran Microbial Metabolism for Colon ChemopreventionR01CA201112 · NCI · COLORADO STATE UNIVERSITY · PI RAINA, KOMAL, RYAN, ELIZABETH P · 2016 to 2020
$1.9M
Rice bran in ready-to-use therapeutic foods for microbiota-targeted treatment of childhood malnutritionR21HD113211 · NICHD · COLORADO STATE UNIVERSITY · PI RYAN, ELIZABETH P · 2023 to 2023
$417k
NCI NIH HHS R01 CA201112NICHD NIH HHS R21 HD113211NIDDK NIH HHS P30 DK048520
6 · The paper itself

Abstract

Dietary rice bran (RB) has shown capacity to influence metabolism by modulation of gut microbiota in individuals at risk for colorectal cancer (CRC), which warranted attention for delineating mechanisms for bidirectional influences and cross-feeding between the host and RB-modified gut microbiota to reduce CRC. Accordingly, in the present study, fermented rice bran (FRB, fermented with a RB responsive microbe Bifidobacterium longum), and non-fermented RB were fed as 10% w/w (diet) to gut microbiota-intact

Indexed as

Bifidobacterium longumGastrointestinal MicrobiomeOryzaAnimalsAzoxymethaneCarcinogenesisCell Transformation, NeoplasticColonDextran SulfateDietDisease Models, AnimalFemaleInflammationMiceMice, Inbred C57BLAzoxymethaneDextran Sulfateazoxymethanecancer interventioncolon carcinogenesisfermentationgerm free micemetabolomicsmicrobiomeprobioticsrice bran

Identifiers

PMID35856887
PMCPMC9474629
OpenAlexW4286001582

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.