Evidence map›Paper›PMID 35856752›Full record

ArticleCutis2022

BRAF V600E Expression in Primary Melanoma and Its Association With Death: A Population-Based, Retrospective, Cross-Sectional Study.

Jamison A Harvey, Julia S Lehman, Christine M Lohse, Alanna M Chamberlain, Svetomir N Markovic, Celine M Vachon, Jerry D Brewer

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cutis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact, top 95% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 0 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 2 countries.

Jamison A HarveyDr. Harvey is from the Department of Dermatology, Mayo Clinic, Scottsdale, Arizona. Drs. Lehman, Chamberlain, Vachon, Markovic, and Brewer and Ms. Lohse are from the Mayo Clinic, Rochester, Minnesota. Drs. Lehman and Brewer are from the Department of Dermatology. Dr. Lehman also is from the Division of Anatomic Pathology. Ms. Lohse and Drs. Chamberlain and Vachon are from the Department of Health Sciences Research.
Julia S LehmanDr. Harvey is from the Department of Dermatology, Mayo Clinic, Scottsdale, Arizona. Drs. Lehman, Chamberlain, Vachon, Markovic, and Brewer and Ms. Lohse are from the Mayo Clinic, Rochester, Minnesota. Drs. Lehman and Brewer are from the Department of Dermatology. Dr. Lehman also is from the Division of Anatomic Pathology. Ms. Lohse and Drs. Chamberlain and Vachon are from the Department of Health Sciences Research.
Christine M LohseDr. Harvey is from the Department of Dermatology, Mayo Clinic, Scottsdale, Arizona. Drs. Lehman, Chamberlain, Vachon, Markovic, and Brewer and Ms. Lohse are from the Mayo Clinic, Rochester, Minnesota. Drs. Lehman and Brewer are from the Department of Dermatology. Dr. Lehman also is from the Division of Anatomic Pathology. Ms. Lohse and Drs. Chamberlain and Vachon are from the Department of Health Sciences Research.
Alanna M ChamberlainDr. Harvey is from the Department of Dermatology, Mayo Clinic, Scottsdale, Arizona. Drs. Lehman, Chamberlain, Vachon, Markovic, and Brewer and Ms. Lohse are from the Mayo Clinic, Rochester, Minnesota. Drs. Lehman and Brewer are from the Department of Dermatology. Dr. Lehman also is from the Division of Anatomic Pathology. Ms. Lohse and Drs. Chamberlain and Vachon are from the Department of Health Sciences Research.
Svetomir N MarkovicDr. Harvey is from the Department of Dermatology, Mayo Clinic, Scottsdale, Arizona. Drs. Lehman, Chamberlain, Vachon, Markovic, and Brewer and Ms. Lohse are from the Mayo Clinic, Rochester, Minnesota. Drs. Lehman and Brewer are from the Department of Dermatology. Dr. Lehman also is from the Division of Anatomic Pathology. Ms. Lohse and Drs. Chamberlain and Vachon are from the Department of Health Sciences Research.
Celine M VachonDr. Harvey is from the Department of Dermatology, Mayo Clinic, Scottsdale, Arizona. Drs. Lehman, Chamberlain, Vachon, Markovic, and Brewer and Ms. Lohse are from the Mayo Clinic, Rochester, Minnesota. Drs. Lehman and Brewer are from the Department of Dermatology. Dr. Lehman also is from the Division of Anatomic Pathology. Ms. Lohse and Drs. Chamberlain and Vachon are from the Department of Health Sciences Research.
Jerry D BrewerDr. Harvey is from the Department of Dermatology, Mayo Clinic, Scottsdale, Arizona. Drs. Lehman, Chamberlain, Vachon, Markovic, and Brewer and Ms. Lohse are from the Mayo Clinic, Rochester, Minnesota. Drs. Lehman and Brewer are from the Department of Dermatology. Dr. Lehman also is from the Division of Anatomic Pathology. Ms. Lohse and Drs. Chamberlain and Vachon are from the Department of Health Sciences Research.
Department of Medical Sciences · BY

Funding

Rochester Epidemiology ProjectR01AG034676 · NIA · MAYO CLINIC ROCHESTER · PI ROCCA, WALTER A, ST SAUVER, JENNIFER LYNN · 2010 to 2019
$9.5M
Interdisciplinary Infrastructure for Aging Research: Rochester Epidemiology ProjectR33AG058738 · NIA · MAYO CLINIC ROCHESTER · PI LEBRASSEUR, NATHAN K, OLSON, JANET E · 2020 to 2022
$2.4M
Interdisciplinary Infrastructure for Aging Research: Rochester Epidemiology ProjectR21AG058738 · NIA · MAYO CLINIC ROCHESTER · PI LEBRASSEUR, NATHAN K, OLSON, JANET E · 2018 to 2019
$437k
NIA NIH HHS R01 AG034676NIA NIH HHS R21 AG058738NIA NIH HHS R33 AG058738
6 · The paper itself

Abstract

Approximately 50% of melanomas contain BRAF mutations; the effects on survival are unclear. We aimed to determine whether mutant BRAF expression in melanoma differs according to age, sex, and melanoma-specific survival. A total of 638 patients who resided in Olmsted County, Minnesota, with a first lifetime diagnosis of melanoma between 1970 and 2009 were identified from the Rochester Epidemiology Project (REP). Available tissue was analyzed for a BRAF V600E mutation with immunohistochemistry.

Indexed as

MelanomaSkin NeoplasmsCross-Sectional StudiesHumansImmunohistochemistryMutationProto-Oncogene Proteins B-rafRetrospective StudiesBRAF protein, humanProto-Oncogene Proteins B-raf

Identifiers

PMID35856752
PMCPMC9846848
OpenAlexW4281621245

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.