Evidence map›Paper›PMID 35856676›Full record

ArticleMicrobiology spectrum2022

Oridonin Attenuates Burkholderia cenocepacia Virulence by Suppressing Quorum-Sensing Signaling.

Xia Li, Kai Wang, Gerun Wang, Binbin Cui, Shihao Song, Xiuyun Sun, Yinyue Deng

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Quorum sensing in theApplied and environmental microbiology · 2026
    Review
  5. Carnosol attenuatesVirulence · 2025
    Article
  6. Review
  7. Signaling inComputational and structural biotechnology journal · 2025
    Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Xia Li *School of Pharmaceutical Sciences (Shenzhen), Shenzhen Campus of Sun Yat-sen Universitygrid.12981.33, Sun Yat-sen University, Shenzhen, China.
Kai Wang *College of Agriculture, South China Agricultural Universitygrid.20561.30, Guangzhou, China.
Gerun Wang *School of Pharmaceutical Sciences (Shenzhen), Shenzhen Campus of Sun Yat-sen Universitygrid.12981.33, Sun Yat-sen University, Shenzhen, China.
Binbin CuiSchool of Pharmaceutical Sciences (Shenzhen), Shenzhen Campus of Sun Yat-sen Universitygrid.12981.33, Sun Yat-sen University, Shenzhen, China.
Shihao SongSchool of Pharmaceutical Sciences (Shenzhen), Shenzhen Campus of Sun Yat-sen Universitygrid.12981.33, Sun Yat-sen University, Shenzhen, China.
Xiuyun SunSchool of Pharmaceutical Sciences (Shenzhen), Shenzhen Campus of Sun Yat-sen Universitygrid.12981.33, Sun Yat-sen University, Shenzhen, China.
Yinyue DengSchool of Pharmaceutical Sciences (Shenzhen), Shenzhen Campus of Sun Yat-sen Universitygrid.12981.33, Sun Yat-sen University, Shenzhen, China.ORCID 0000-0003-1511-0870
Sun Yat-sen University · CNSouth China Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Burkholderia cenocepacia is a human opportunistic pathogen that mostly employs two types of quorum-sensing (QS) systems to regulate its various biological functions and pathogenicity: the

Indexed as

Burkholderia cenocepaciaAcyl-ButyrolactonesBacterial ProteinsDiterpenes, KauraneGene Expression Regulation, BacterialHumansQuorum SensingVirulenceAcyl-ButyrolactonesBacterial ProteinsDiterpenes, KauraneoridoninAHLBDSFBurkholderia cenocepaciaoridoninquorum sensing

Identifiers

PMID35856676
PMCPMC9430380
OpenAlexW4286210433

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.