Evidence map›Paper›PMID 35856657›Full record

ArticlemBio2022

Secondary Metabolites Produced during Aspergillus fumigatus and Pseudomonas aeruginosa Biofilm Formation.

Rafael Wesley Bastos, Daniel Akiyama, Thaila Fernanda Dos Reis, Ana Cristina Colabardini, Rafael Sanchez Luperini, Patrícia Alves de Castro, Regina Lúcia Baldini, Taícia Fill, Gustavo H Goldman

Open access · goldAbstract read
In one paragraph

Article in mBio, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Role of Iron Availability in ModulatingJournal of fungi (Basel, Switzerland) · 2026
    Article
  5. BioMed research international · 2026
    Review
  6. Review
  7. Review
  8. Review
  9. mBio · 2025
    Article
  10. Antagonistic effect ofFrontiers in fungal biology · 2025
    Article
  11. The pathobiology of human fungal infections.Nature reviews. Microbiology · 2024
    Review
  12. Mutation ofMicrobiology spectrum · 2024
    Article
  13. Review
  14. Convergent evolution in toxin detection and resistance provides evidence for conserved bacterial-fungal interactions.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  15. Article
  16. Antifungal potential of multi-drug-resistantFrontiers in cellular and infection microbiology · 2024
    Article
  17. Article
  18. Article
  19. Journal of fungi (Basel, Switzerland) · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Rafael Wesley BastosFaculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, Brazil.
Daniel AkiyamaInstituto de Química, Universidade Estadual de Campinas, Campinas, Brazil.
Thaila Fernanda Dos ReisFaculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, Brazil.
Ana Cristina ColabardiniFaculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, Brazil.
Rafael Sanchez LuperiniFaculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, Brazil.
Patrícia Alves de CastroFaculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, Brazil.
Regina Lúcia BaldiniDepartamento de Bioquímica, Instituto de Química, Universidade de São Paulo, São Paulo, Brazil.ORCID 0000-0003-4349-6352
Taícia FillInstituto de Química, Universidade Estadual de Campinas, Campinas, Brazil.
Gustavo H GoldmanFaculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, Brazil.ORCID 0000-0002-2986-350X
Universidade de São Paulo · BRUniversidade Estadual de Campinas (UNICAMP) · BR

Funding

Deciphering the phenotypic and genomic traits that underlie the evolution of pathogenicity differences among Aspergillus fumigatus and its close relativesR01AI153356 · NIAID · VANDERBILT UNIVERSITY · PI Antonis Rokas · 2022 to 2026
$3.5M
NIAID NIH HHS R01 AI153356
6 · The paper itself

Abstract

In cystic fibrosis (CF), mucus plaques are formed in the patient's lungs, creating a hypoxic condition and a propitious environment for colonization and persistence of many microorganisms. There is clinical evidence showing that Aspergillus fumigatus can cocolonize CF patients with Pseudomonas aeruginosa, which has been associated with lung function decline. P. aeruginosa produces several compounds with inhibitory and antibiofilm effects against A. fumigatus

Indexed as

Cystic FibrosisGliotoxinAspergillus fumigatusBiofilmsHumansHypoxiaPhenazinesPseudomonas aeruginosaGliotoxinPhenazinesAspergillus fumigatusbiofilm formationgliotoxinhypoxia and normoxiaPseudomonas aeruginosasecondary metabolites

Identifiers

PMID35856657
PMCPMC9426470
OpenAlexW4286210608

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.