Evidence map›Paper›PMID 35856562›Full record

ArticlemBio2022

Glucose-1,6-Bisphosphate, a Key Metabolic Regulator, Is Synthesized by a Distinct Family of α-Phosphohexomutases Widely Distributed in Prokaryotes.

Niels Neumann, Simon Friz, Karl Forchhammer

Open access · goldAbstract read
In one paragraph

Article in mBio, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Phosphoglucomutase comes into the spotlight.Journal of experimental botany · 2023
    Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Niels NeumannInterfaculty Institute of Microbiology and Infection Medicine, University of Tübingengrid.10392.39, Tübingen, Germany.ORCID 0000-0001-6185-1368
Simon FrizInterfaculty Institute of Microbiology and Infection Medicine, University of Tübingengrid.10392.39, Tübingen, Germany.
Karl ForchhammerInterfaculty Institute of Microbiology and Infection Medicine, University of Tübingengrid.10392.39, Tübingen, Germany.ORCID 0000-0003-3199-8101
German Center for Infection Research · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The reactions of α-d-phosphohexomutases (αPHM) are ubiquitous, key to primary metabolism, and essential for several processes in all domains of life. The functionality of these enzymes relies on an initial phosphorylation step which requires the presence of α-d-glucose-1,6-bisphosphate (Glc-1,6-BP). While well investigated in vertebrates, the origin of this activator compound in bacteria is unknown. Here we show that the Slr1334 protein from the unicellular cyanobacterium

Indexed as

Glucose-6-PhosphatePhosphoglucomutaseAnimalsGlucoseHumansPhylogenyGlucoseglucose-1,6-bisphosphateGlucose-6-PhosphatePhosphoglucomutasecarbon metabolismglucose-1,6-bisphosphateglycolysisphosphoglucomutase

Identifiers

PMID35856562
PMCPMC9426568
OpenAlexW4286001362

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.