Evidence map›Paper›PMID 35856072›Full record

ArticlePeerJ analytical chemistry2022

Determination of optical density (OD) of oligodeoxynucleotide from HPLC peak area.

Komal Chillar, Yipeng Yin, Adikari M Dhananjani N Eriyagama, Shiyue Fang

Abstract read
In one paragraph

Article in PeerJ analytical chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Oligonucleotide synthesis under mild deprotection conditions.New journal of chemistry = Nouveau journal de chimie · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Komal ChillarDepartment of Chemistry, Michigan Technological University, Houghton, MI, United States.
Yipeng YinDepartment of Chemistry, Michigan Technological University, Houghton, MI, United States.
Adikari M Dhananjani N EriyagamaDepartment of Chemistry, Michigan Technological University, Houghton, MI, United States.
Shiyue FangDepartment of Chemistry, Michigan Technological University, Houghton, MI, United States.

Funding

Synthesis of Sensitive Epitranscriptomically Modified RNAsR15GM109288 · NIGMS · MICHIGAN TECHNOLOGICAL UNIVERSITY · PI FANG, SHIYUE · 2014 to 2024
$1.3M
NIGMS NIH HHS R15 GM109288
6 · The paper itself

Abstract

Oligodeoxynucleotides (ODNs) are typically purified and analysed with HPLC equipped with a UV-Vis detector. Quantities of ODNs are usually determined using a UV-Vis spectrometer separately after HPLC, and are reported as optical density at 260 nm (OD

Indexed as

Analytical Chemistry (other)HPLCNovel Analytical TechnologiesODOligonucleotideOptical densityQuantificationSample HandlingSpectroscopic AnalysisUV-Visible Spectroscopy

Identifiers

PMID35856072
PMCPMC9288849

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.