Evidence map›Paper›PMID 35856016›Full record

ArticlemicroPublication biology2022

Pre-adult exposure to three heavy metals leads to changes in the head transcriptome of adult flies.

Kenton R Felmlee, Stuart J Macdonald, Elizabeth R Everman

Open access · greenAbstract read
In one paragraph

Article in microPublication biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Kenton R FelmleeDepartment of Molecular Biosciences, University of Kansas.
Stuart J MacdonaldDepartment of Molecular Biosciences, University of Kansas; Center for Computational Biology, University of Kansas.
Elizabeth R EvermanDepartment of Molecular Biosciences, University of Kansas.
University of Kansas · US

Funding

Mentoring CoreP20GM103418 · NIGMS · UNIVERSITY OF KANSAS MEDICAL CENTER · PI SUSAN J. BROWN · 2012 to 2026
$63.0M
Understanding the mechanobiology of stem cells in a microengineered 3D cardiac tissue environment with cardiomyopathyP20GM103638 · NIGMS · UNIVERSITY OF KANSAS LAWRENCE · PI LUNTE, SUSAN M · 2012 to 2021
$22.1M
Synthetic Chemical Biology CoreP30GM145499 · NIGMS · UNIVERSITY OF KANSAS LAWRENCE · PI Susan M Lunte · 2022 to 2026
$6.9M
A resource for the genetic analysis of complex traitsR01OD010974 · OD · UNIVERSITY OF KANSAS LAWRENCE · PI LONG, ANTHONY DOUGLAS, MACDONALD, STUART JOHN · 2012 to 2019
$3.1M
Toxicogenomics of metal response in genetically-variable DrosophilapopulationsR01ES029922 · NIEHS · UNIVERSITY OF KANSAS LAWRENCE · PI MACDONALD, STUART JOHN · 2019 to 2021
$682k
Linking genomic, physiological, and behavioral responses using a Drosophila model of heavy metal stressK99ES033257 · NIEHS · UNIVERSITY OF KANSAS LAWRENCE · PI EVERMAN, ELIZABETH · 2021 to 2022
$180k
NIEHS NIH HHS K99 ES033257NIEHS NIH HHS R01 ES029922NIGMS NIH HHS P20 GM103418NIGMS NIH HHS P20 GM103638NIGMS NIH HHS P30 GM145499NIH HHS R01 OD010974
6 · The paper itself

Abstract

We examined the effect of developmental exposure to three heavy metals - cadmium, copper, and lead - on gene expression in adult head tissue in the model organism

Identifiers

PMID35856016
PMCPMC9287740
OpenAlexW4286376446

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.