Observational studyPeerJ2022
Oxygen uptake efficiency slope in healthy normal weight young males: an applicable framework for calculation and interpretation.
Observational study in PeerJ, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed, 3 citations in OpenAlex.
- Cardiopulmonary Exercise Testing Reveals Functional Limitations and Work Disability in Severe Post-COVID-19 and ME/CFS Patients.Sports medicine - open · 2026Article
- Alterations in submaximal cardiopulmonary indicators in CVD patients participating in APBCRE-a comprehensive CPET-based study.Frontiers in cardiovascular medicine · 2026Article
- Comparative Contributions of Oxygen Uptake Efficiency and Maximal Oxygen Uptake to Fat Oxidation Metrics in Healthy Male Adults.Sports medicine - open · 2025Article
- Hyperventilation during rest and exercise in orthostatic intolerance and Spiky-Leaky Syndrome.Frontiers in neurology · 2025Article
Corrections and comments
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Authors and funding
5 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The oxygen uptake efficiency slope (OUES) is considered a reliable indicator of cardiorespiratory fitness in young and clinical populations who cannot achieve maximal effort during a graded exercise test. However, OUES accuracy depends on the data points used for its calculation and it is still not clear if the submaximal OUES can accurately assess CRF in healthy young males. Objective: We investigated the association between peak oxygen uptake and peak and submaximal OUES, and the agreement between submaximal OUES and peak OUES in male adolescents and young adults. Methods: In this cross-sectional, observational study, fifty normal weight healthy participants (age 14-22 years, peak oxygen uptake 43.8 ± 7.3 mL·min Results: Very strong correlations were observed between peak oxygen uptake and peak OUES ( Conclusions: . The peak OUES is a better indicator of aerobic fitness than the OUES up to the anaerobic threshold in healthy, young males. The OUES up to the anaerobic threshold is a valid alternative to peak OUES.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.