Evidence map›Paper›PMID 35855887›Full record

ArticleJournal of ophthalmology2022

Long-Term Effect of Anti-Vascular Endothelial Growth Factor (Anti-VEGF) Injections in Choroidal Neovascularization Secondary to Angioid Streaks.

Sónia Torres-Costa, João Bernardes, Sofia Sousa Mano, Joana Medeiros-Pinto, Ana Carolina Abreu, Maria João Furtado, Rufino Silva, Carlos Marques-Neves, Fernando Falcão-Reis, Ângela Carneiro and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of ophthalmology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 1 country.

Sónia Torres-CostaDepartment of Ophthalmology, Centro Hospitalar Universitário de São João, Porto, Portugal.ORCID https://orcid.org/0000-0002-7079-9554
João BernardesDepartment of Ophthalmology, Centro Hospitalar Universitário de Coimbra, Coimbra, Portugal.
Sofia Sousa ManoDepartment of Ophthalmology, Centro Hospitalar Universitário Lisboa Norte, Lisboa, Portugal.
Joana Medeiros-PintoDepartment of Ophthalmology, Centro Hospitalar Universitário Lisboa Norte, Lisboa, Portugal.
Ana Carolina AbreuDepartment of Ophthalmology, Centro Hospitalar Universitário Do Porto, Porto, Portugal.
Maria João FurtadoDepartment of Ophthalmology, Centro Hospitalar Universitário Do Porto, Porto, Portugal.
Rufino SilvaDepartment of Ophthalmology, Centro Hospitalar Universitário de Coimbra, Coimbra, Portugal.
Carlos Marques-NevesDepartment of Ophthalmology, Centro Hospitalar Universitário Lisboa Norte, Lisboa, Portugal.ORCID https://orcid.org/0000-0002-3842-2466
Fernando Falcão-ReisDepartment of Ophthalmology, Centro Hospitalar Universitário de São João, Porto, Portugal.
Ângela CarneiroDepartment of Ophthalmology, Centro Hospitalar Universitário de São João, Porto, Portugal.
Luísa ColaçoDepartment of Ophthalmology, Centro Hospitalar Fernando da Fonseca, Amadora, Portugal.
Manuel FalcãoDepartment of Ophthalmology, Centro Hospitalar Universitário de São João, Porto, Portugal.ORCID https://orcid.org/0000-0003-4718-0910
Universidade do Porto · PTCentro Hospitalar do Porto · PTCentro Hospitalar Lisboa Norte · PTHospitais da Universidade de Coimbra · PTHospital de São João · PTHospital Prof. Dr. Fernando Fonseca · PTUniversity of Lisbon · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: This study aimed to evaluate the long-term effectiveness of intravitreal anti-vascular endothelial growth factor (VEGF) injections in the treatment of choroidal neovascularization (CNV) associated with angioid streaks. Methods: Multicenter retrospective cohort study, including eyes with CNV secondary to angioid streaks treated with anti-VEGF injections, were performed. Best-corrected visual acuity (BCVA) in ETDRS letters; qualitative and quantitative (foveal thickness) OCT parameters; anti-VEGF type; and number of injections were collected at baseline and at 3, 6, 12, 24, 36, 48, 60, and 72 months. Results: Thirty-nine eyes from 29 patients, 17 (58.6%) females, were included. The mean follow-up time was 69.4 ± 34.5 months. BCVA was 59.3 ± 23.3 letters at baseline and 63.7 ± 21.9 letters at 48 months. At 3 months, BCVA improved 6.9 ± 11.7 letters ( Conclusion: This real-world study suggests that the functional and morphologic response to anti-VEGF therapy for CNV related to angioid streaks is generally satisfactory and maintained in the long term.

Identifiers

PMID35855887
PMCPMC9288306
OpenAlexW4284977442

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.