Evidence map›Paper›PMID 35855884›Full record

ReviewAnnals of medicine and surgery (2012)2022

Pulmonary AL amyloidosis: A review and update on treatment options.

Lindsay N Moy, Mahum Mirza, Blake Moskal, Nahren Asado, Bhaven Shah, Jacob Bitran

Open access · diamondAbstract readReview
In one paragraph

Review in Annals of medicine and surgery (2012), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Pulmonary amyloidosis: a case report.Oxford medical case reports · 2025
    Article
  7. Article
  8. Multifocal pulmonary amyloidosis mimicking metastases.Lung India : official organ of Indian Chest Society · 2025
    Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Lindsay N MoyDepartment of Internal Medicine at Advocate Lutheran General Hospital (ALGH), United States.
Mahum MirzaDepartment of Internal Medicine at Advocate Lutheran General Hospital (ALGH), United States.
Blake MoskalDepartment of Internal Medicine at Advocate Lutheran General Hospital (ALGH), United States.
Nahren AsadoDepartment of Pathology at ALGH, United States.
Bhaven ShahDepartment of Pulmonology and Critical Care Medicine at ALGH, United States.
Jacob BitranDepartment of Hematology and Oncology at ALGH, United States.
Advocate Lutheran General Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Amyloidosis is a rare disease that involves the extracellular deposition of abnormally folded proteins, precipitating organ dysfunction. Pulmonary amyloidosis is frequently characterized by the AL amyloid subtype and can be localized or associated with systemic involvement, presenting in a nodular, diffuse alveolar-septal, or tracheobronchial pattern. Presentation of disease can vary from clinically silent to severe. Pulmonary amyloidosis is typically first suspected on CT scan of the chest. Diagnostic workup requires tissue biopsy and identification by immunohistochemical staining. Systemic treatment has evolved over recent years to include the combination of daratumumab, bortezomib, cyclophosphamide, and dexamethasone (dara-VCD) as first-line therapy, with the goal of quickly attaining complete hematologic response. Through clinical vignettes, we review pulmonary AL amyloidosis and discuss current treatment options.

Indexed as

AL amyloidPulmonary amyloidosis

Identifiers

PMID35855884
PMCPMC9287433
OpenAlexW4284969203

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.