Evidence map›Paper›PMID 35855763›Full record

ArticleCancer management and research2022

Stereotactic Body Radiotherapy for Locally Advanced Pancreatic Cancer Using Optical Surface Management System - AlignRT as an Optical Body Surface Motion Management in Deep Breath Hold Patients: Results from a Single-Arm Retrospective Study.

Hrvoje Kaučić, Domagoj Kosmina, Dragan Schwarz, Andreas Mack, Adlan Čehobašić, Vanda Leipold, Asmir Avdićević, Mihaela Mlinarić, Matea Lekić, Karla Schwarz and 1 more

Open access · goldAbstract read
In one paragraph

Article in Cancer management and research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Hrvoje KaučićDepartment of Radiosurgery and Radiotherapy, Special Hospital Radiochirurgia Zagreb, Sveta Nedelja, Croatia.ORCID 0000-0002-9451-1762
Domagoj KosminaDepartment of Medical Physics, Special Hospital Radiochirurgia Zagreb, Sveta Nedelja, Croatia.ORCID 0000-0002-4099-9002
Dragan SchwarzDepartment of Surgery, Special Hospital Radiochirurgia Zagreb, Sveta Nedelja, Croatia.ORCID 0000-0002-4421-0865
Andreas MackSwiss NeuroRadiosurgery Center, Swiss Clinical NeuroScience Institute, Zürich, Switzerland.ORCID 0000-0001-7591-4374
Adlan ČehobašićUniversity Josip Juraj Strossmayer in Osijek - Medical Faculty Osijek, Osijek, Croatia.ORCID 0000-0001-8556-3280
Vanda LeipoldUniversity Josip Juraj Strossmayer in Osijek - Medical Faculty Osijek, Osijek, Croatia.ORCID 0000-0003-2338-8119
Asmir AvdićevićDepartment of Radiosurgery and Radiotherapy, Special Hospital Radiochirurgia Zagreb, Sveta Nedelja, Croatia.ORCID 0000-0002-0619-1587
Mihaela MlinarićDepartment of Medical Physics, Special Hospital Radiochirurgia Zagreb, Sveta Nedelja, Croatia.ORCID 0000-0002-6362-473X
Matea LekićDepartment of Radiosurgery and Radiotherapy, Special Hospital Radiochirurgia Zagreb, Sveta Nedelja, Croatia.ORCID 0000-0001-7282-1869
Karla SchwarzUniversity of Zagreb, Medical Faculty, Zagreb, Croatia.ORCID 0000-0001-9278-660X
Marija BanovićDepartment of Endocrinology, Polyclinic Leptir, Zagreb, Croatia.ORCID 0000-0001-8291-4313
Croatian Academic and Research Network · HRUniversity of Osijek · HRUniversity Hospital Centre Zagreb · HRUniversity of Zagreb · HR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To assess the efficacy and safety of stereotactic body radiotherapy for patients with unresectable, locally advanced pancreatic cancer using Optical Surface Management System - AlignRT (OSMS-AlignRT) as an optical body surface motion management in deep breath hold. Patients and Methods: Forty-five patients diagnosed with locally advanced pancreatic cancer were treated with stereotactic body radiotherapy in 3 or 5 fractions, and received varying BED Results: Data from forty-five patients were analyzed. Median follow-up was 15 months. One-year freedom from local progression and survival were 95.5% and 71.1%, respectively. Median progression-free survival was 14 months. Median overall survival from diagnosis for all patients was 17 months, and 19 months for patients alive at the time of analysis. No patient had >G2 toxicity. Conclusion: Stereotactic body radiotherapy for locally advanced pancreatic cancer using OSMS-AlignRT as optical body surface motion management in deep breath hold patients is an effective and safe local treatment option, with no >G2 toxicity, and could be a promising therapeutic option with acceptable toxicity, either as a single treatment or in a multimodal regimen. OSMS-AlignRT provided accurate and reliable body surface motion management during stereotactic body radiotherapy.

Indexed as

AlignRTlocally advanced pancreatic cancerOptical Surface Management Systempancreatic SBRTsurface guided radiotherapy

Identifiers

PMID35855763
PMCPMC9288179
OpenAlexW4285008637

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.