Evidence map›Paper›PMID 35855758›Full record

ArticleInfection and drug resistance2022

Rapid Detection of Carbapenem-Resistant

Jinyu Wang, Cuiping Xia, Yue Wu, Xin Tian, Ke Zhang, Zhongxin Wang

Abstract read
In one paragraph

Article in Infection and drug resistance, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Artificial intelligence in antimicrobial stewardship: a systematic review and meta-analysis of predictive performance and diagnostic accuracy.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
    Pooled it
  3. Review
  4. Article
  5. Prediction of KPC-producingJournal of clinical microbiology · 2026
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Classification ofMicrobiology spectrum · 2024
    Article
  13. Review
  14. Review
  15. Machine learning model of imipenem-resistantHealth science reports · 2023
    Article
  16. Differentiation betweenInternational journal of molecular sciences · 2023
    Article
  17. Article
  18. Rapid discrimination ofFrontiers in microbiology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jinyu Wang *Department of Clinical Laboratory, The First Affiliated Hospital of Anhui Medical University, Hefei, People's Republic of China.ORCID 0000-0001-6636-7831
Cuiping Xia *Department of Clinical Laboratory, The First Affiliated Hospital of Anhui Medical University, Hefei, People's Republic of China.
Yue WuDepartment of Clinical Laboratory, The First Affiliated Hospital of Anhui Medical University, Hefei, People's Republic of China.
Xin TianDepartment of Clinical Laboratory, The First Affiliated Hospital of Anhui Medical University, Hefei, People's Republic of China.
Ke ZhangDepartment of Clinical Laboratory, The First Affiliated Hospital of Anhui Medical University, Hefei, People's Republic of China.
Zhongxin WangDepartment of Clinical Laboratory, The First Affiliated Hospital of Anhui Medical University, Hefei, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Rapid detection of carbapenem-resistant Methods: Clinically collected Results: The RF, SVM and SVM-K models showed good classification performance with 0.88, 0.88, and 0.91 accuracy, 0.82, 0.85, and 0.89 sensitivity, 0.93, 0.92, and 0.94 specificity with an AUC of 0.9013, 0.9298, and 0.9356, respectively. For the SVM-K model, the optimal dimension reduction was 105 to 153, and the average accuracy was >0.9. The top 10 peak features of significance according to the RF algorithm with 6515 Da appeared in 56.8% of CRKP isolates and 5.3% of CSKP isolates, which indicated the best classification performance. Conclusion: The three RF, SVM, and SVM-K models showed excellent classification performance differentiating the CRKP from CSKP; the SVM-K model was the best. Data analysis with machine learning combined with MALDI-TOF MS can be employed as a rapid and inexpensive alternative to existing detection methods.

Indexed as

Klebsiella pneumoniaeMALDI-TOF MSRFSVMSVM-K

Identifiers

PMID35855758
PMCPMC9288218

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.