ArticleEuropean eating disorders review : the journal of the Eating Disorders Association2022
Association of autism diagnosis and polygenic scores with eating disorder severity.
Article in European eating disorders review : the journal of the Eating Disorders Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 34 citations in OpenAlex.
- A scoping review of the relationship between autistic traits and eating disorders: exploring the secondary impact of eating disorders and co-occurring psychiatric diagnoses.Frontiers in psychiatry · 2026Pooled it
- A Mixed Method Systematic Review Into the Impact of ED Treatment in Autistic People and Those With High Autistic Traits.The International journal of eating disorders · 2025Pooled it
- Digital augmentation of aftercare for patients with anorexia nervosa: the TRIANGLE RCT and economic evaluation.Health technology assessment (Winchester, England) · 2025Trial
- Considering Autism in Binge-Type Eating Disorders: Broadening Beyond an Anorexia Nervosa-Focused Model.Current psychiatry reports · 2026Review
- Psychiatric Morbidity Is Overrepresented in Young Girls at High Risk of Developing Anorexia Nervosa.The International journal of eating disorders · 2026Article
- Time to notice neurodiversity in eating disorder services: a three-year real-world analysis of autism, ADHD, and AuDHD.Frontiers in psychiatry · 2026Article
- Systematic Review and Meta-Analysis: Phenotypic Correlates of the Autism Polygenic Score.JAACAP open · 2025Article
- Long-acting injectable paliperidone palmitate for severe anorexia nervosa and comorbid autism spectrum disorder: A case report.PCN reports : psychiatry and clinical neurosciences · 2025Article
- Eating Disorder and Autism Collaborative project outline: promoting eating disorder research embedded in a neurodiversity-affirming culture.BJPsych bulletin · 2025Review
- Understanding the child and adolescent eating disorder treatment experiences of autistic people and parents.Journal of eating disorders · 2025Article
- "From That Moment, Everything has Changed": The Experience of Women With Anorexia Nervosa Receiving a Diagnosis of Autism.European eating disorders review : the journal of the Eating Disorders Association · 2025Article
- Autism, ADHD, and Their Traits in Adults With Bulimia Nervosa and Binge Eating Disorder: A Scoping Review.European eating disorders review : the journal of the Eating Disorders Association · 2025Article
- Eating Behaviors of Autistic Women with an Eating Disorder.Nutrients · 2025Article
- The Cognitive Profile in Adolescents With Anorexia Nervosa and the Relationship With Autism and ADHD: A Pilot Study.European eating disorders review : the journal of the Eating Disorders Association · 2025Article
- Article
- Interrater reliability of the DSM-5 and ICD-11 Criterion A for PTSD and complex PTSD in parents of children with autism using the Life Events Checklist.BJPsych open · 2025Article
- Barriers and facilitators to ethical co-production with Autistic people with an eating disorder.Journal of eating disorders · 2024Article
- Inclusion of the severe and enduring anorexia nervosa phenotype in genetics research: a scoping review.Journal of eating disorders · 2024Article
- The impact of genetic risk for schizophrenia on eating disorder clinical presentations.Translational psychiatry · 2023Article
- Association of autism diagnosis and polygenic scores with eating disorder severity.European eating disorders review : the journal of the Eating Disorders Association · 2022Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
Abstract
Among individuals with eating disorders (ED), those with co-occurring autism are often considered to have more severe presentations and poorer prognosis. However, previous findings have been contradictory and limited by small sample size and/or cross-sectional assessment of autistic traits. We examine the hypothesis that autism diagnosis and autism polygenic score (PGS) are associated with increased ED severity in a large ED cohort using a broad range of ED severity indicators. Our cohort included 3189 individuals (64 males) born 1977-2000 with current or previous anorexia nervosa who participated in the Anorexia Nervosa Genetics Initiative-Sweden (ANGI-SE) and for whom genotypes and linkage to national registers were available. We identified 134 (4.2%) individuals with registered autism diagnoses. Individuals with confirmed autism diagnosis had significantly more severe ED across three sets of severity indicators. Some of the largest effects were found for the proportion of individuals who attempted suicide and who received tube feeding (higher in autism), and for the time spent in inpatient care (longer in autism). Results for autism PGS were not statistically significant. Adapting ED treatment to the needs of individuals with co-occurring autism is an important research direction to improve treatment outcome in this group.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.