Evidence map›Paper›PMID 35855155›Full record

ArticleSurgical neurology international2022

Extensive spontaneous cervical epidural hematoma due to oral anticoagulant (dabigatran) successfully treated with reversal agent idarucizumab alone.

Syed-Abdullah Uddin, Katerina Roma, Lindsey Ross, George Hanna, Doniel Drazin, Terrence T Kim

Open access · hybridAbstract readCase Reports
In one paragraph

Article in Surgical neurology international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Syed-Abdullah UddinDepartment of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, California.
Katerina RomaDepartment of Neurosurgery, Pacific Northwest University of Health Sciences, Yakima, Washington.
Lindsey RossDepartment of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, California.
George HannaDepartment of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, California.
Doniel DrazinDepartment of Neurosurgery, Pacific Northwest University of Health Sciences, Yakima, Washington.
Terrence T KimCedars-Sinai Medical Center, Spine Center, Los Angeles, California, United States.
Cedars-Sinai Medical Center · USPacific Northwest University of Health Sciences · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Dabigatran is an anticoagulant (novel oral anticoagulant) that is a direct thrombin inhibitor and only recently has a reversal agent, idarucizumab, been made available (2015). Case Description: An 86-year-old male taking dabigatran for atrial fibrillation, acutely presented with the spontaneous onset of neck pain and quadriparesis. When the MRI demonstrated a C2-T2 spinal epidural hematoma, the patient was given the reversal agent idarucizumab. Due to his attendant major comorbidities, he was managed nonoperatively. Over the next 7 days, the patient's neurological deficits resolved, and within 2 weeks, he had regained normal neurological function. Conclusion: In this case, a C2-T2 epidural cervical hematoma attributed to dabigatran that was responsible for an acute, spontaneous quadriparesis was successfully treated with the reversal agent idarucizumab without surgical intervention being warranted.

Indexed as

Anticoagulant reversalDabigatranIdarucizumabPradaxaSpinal epidural hematoma

Identifiers

PMID35855155
PMCPMC9282756
OpenAlexW4283455060

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.