Evidence map›Paper›PMID 35855152›Full record

ArticleSurgical neurology international2022

Early versus delayed debridement for surgical site infection after oncological neurosurgery.

Joao Paulo Mota Telles, Vitor Nagai Yamaki, Ricardo Andrade Caracante, Victor Hugo Barboza Martins, Wellingson Silva Paiva, Manoel Jacobsen Teixeira, Eberval Gadelha Figueiredo, Iuri Santana Neville

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In one paragraph

Article in Surgical neurology international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Joao Paulo Mota TellesDepartment of Neurology, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Brazil.
Vitor Nagai YamakiDepartment of Neurosurgery, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Brazil.
Ricardo Andrade CaracanteDepartment of Radiology, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Brazil.
Victor Hugo Barboza MartinsDepartment of Neurosurgery, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Brazil.
Wellingson Silva PaivaDepartment of Neurology University of Sao Paulo, Sao Paulo, Brazil.
Manoel Jacobsen TeixeiraDepartment of Neurosurgery, University of Sao Paulo, Sao Paulo, Brazil.
Eberval Gadelha FigueiredoDepartment of Neurosurgery, University of Sao Paulo, Sao Paulo, Brazil.
Iuri Santana NevilleDepartment of Neurosurgery, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Brazil.
Universidade de São Paulo · BRHospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: There are no guidelines on the management of surgical site infection (SSI) in neurosurgery. This study sought to analyze whether early debridement improved survival compared to antibiotic therapy alone in patients with postcraniotomy infections after oncological neurosurgeries. Methods: We retrospectively reviewed patient records from 2011 to 2019 to identify patients that had been reoperated for the debridement of SSI after brain tumor resection. If SSI was suspected but not clinically evident, the diagnosis was confirmed by cerebrospinal fluid (CSF) analysis or contrast-based imaging examinations. Immediately after diagnosis, broad-spectrum antibiotics were started for all patients. Results: Out of 81 SSI cases, 57 underwent debridement. Two patients were reoperated 3 times, and three had two surgeries, resulting in a total of 64 procedures. The number of days between SSI diagnosis and surgical intervention did not influence mortality in both univariate and multivariable analyses (Hazard ratio [HR] 1.03, 95% CI 0.93-1.13). Early debridement (<24 h) did not influence rates of antibiotic prescription at discharge ( Conclusion: Early debridement does not seem to influence the survival, rates of antibiotic at discharge, or hospital LOS of patients presenting with SSI after neurosurgery for intracranial tumors. High NLRs are strong predictors of worse prognosis in this population.

Indexed as

Antibacterial agentsBrain neoplasmsDebridementSurgical wound infectionsSurvival analysis

Identifiers

PMID35855152
PMCPMC9282797
OpenAlexW4283766881

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.