Evidence map›Paper›PMID 35855064›Full record

ArticleGlobal health & medicine2022

Exploratory study on relative dose intensity and reasons for dose reduction of adjuvant CAPOX therapy in elderly patients with colorectal cancer.

Ayumi Tsuchiya, Chiaki Ogawa, Naoki Kondo, Yasushi Kojima, Yasuhide Yamada, Hiroyuki Terakado

Open access · bronzeAbstract read
In one paragraph

Article in Global health & medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ayumi TsuchiyaPharmaceutical Department, Center Hospital of the National Center for Global Health and Medicine, Tokyo, Japan.
Chiaki OgawaPharmaceutical Department, Center Hospital of the National Center for Global Health and Medicine, Tokyo, Japan.
Naoki KondoPharmaceutical Department, Center Hospital of the National Center for Global Health and Medicine, Tokyo, Japan.
Yasushi KojimaGastroenterology, Center Hospital of the National Center for Global Health and Medicine, Tokyo, Japan.
Yasuhide YamadaComprehensive Cancer Center, Center Hospital of the National Center for Global Health and Medicine, Tokyo, Japan.
Hiroyuki TerakadoPharmaceutical Department, Center Hospital of the National Center for Global Health and Medicine, Tokyo, Japan.
National Center for Global Health and Medicine · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Capecitabine plus oxaliplatin, CAPOX, therapy is one of the standardized options for adjuvant chemotherapy for colorectal cancer, but the efficacy and the safety of CAPOX in elderly patients are unclear. In this study, we investigated the relative dose intensity (RDI) and reasons for dose reduction in patients over the age of 70 (elderly group) (

Indexed as

hematologic toxicityover the age of 70oxaliplatinperipheral neuropathytherapeutic intensity

Identifiers

PMID35855064
PMCPMC9243406
OpenAlexW4205899817

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.