Evidence map›Paper›PMID 35855001›Full record

ArticleOpen forum infectious diseases2022

Incidences of Infectious Events in a Renal Transplant Cohort of the German Center of Infectious Diseases (DZIF).

Claudia Sommerer, Iris Schröter, Katrin Gruneberg, Daniela Schindler, Rouven Behnisch, Christian Morath, Lutz Renders, Uwe Heemann, Paul Schnitzler, Anette Melk and 7 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Open forum infectious diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06346665 (The Transplant Cohort of the German Center for Infection Research), which is not on this map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06346665 recruitingnot on this map

The Transplant Cohort of the German Center for Infection Research

Typeobservational_patient_registrySponsorTechnical University of MunichRan2016 to 2030Enrolled3,000ConditionsInfections, Transplant Complication, Transplant Failure, Immunosuppression
3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 23 citations in OpenAlex.

  1. Trial
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  6. Findings and significance of early follow-up biopsies after treatment of acute rejection in kidney transplant recipients.Transplant international : official journal of the European Society for Organ Transplantation · 2026
    Article
  7. Article
  8. Guiding Antiviral Cell Therapy Approaches with an Online Resource of Clinically Scored Epitopes, T-Cell Receptors, and B-Cell Receptors.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2025
    Article
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  11. Age-Related Risk After Kidney Transplantation: A Comprehensive Analysis of Infection Burden, Graft Outcomes, and Mortality.Transplant international : official journal of the European Society for Organ Transplantation · 2025
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  19. Impact of Repeated Non-Fatal Infections on Quality of Life and Graft Function in ABO-Incompatible Kidney Transplants.Transplant infectious disease : an official journal of the Transplantation Society
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 5 institutions in 1 country.

Claudia SommererNephrology, University Hospital Heidelberg, Heidelberg, Germany.
Iris SchröterNephrology, University Hospital Heidelberg, Heidelberg, Germany.
Katrin GrunebergNephrology, University Hospital Heidelberg, Heidelberg, Germany.
Daniela SchindlerGerman Centre for Infection Research (DZIF), Germany.
Rouven BehnischInstitute of Medical Biometry, University Hospital Heidelberg, Heidelberg, Germany.
Christian MorathNephrology, University Hospital Heidelberg, Heidelberg, Germany.
Lutz RendersGerman Centre for Infection Research (DZIF), Germany.
Uwe HeemannGerman Centre for Infection Research (DZIF), Germany.
Paul SchnitzlerGerman Centre for Infection Research (DZIF), Germany.
Anette MelkGerman Centre for Infection Research (DZIF), Germany.
Andrea Della PennaDepartment of General, Visceral and Transplant Surgery, University Hospital Tuebingen, Tuebingen, Germany.
Silvio NadalinGerman Centre for Infection Research (DZIF), Germany.
Klaus HeegGerman Centre for Infection Research (DZIF), Germany.
Stefan MeuerGerman Centre for Infection Research (DZIF), Germany.
Martin ZeierNephrology, University Hospital Heidelberg, Heidelberg, Germany.
Thomas GieseGerman Centre for Infection Research (DZIF), Germany.
Transplant Cohort of the German Center for Infection Research (DZIF Transplant Cohort) Consortium
German Center for Infection Research · DEUniversity Hospital Heidelberg · DEHeidelberg University · DEKlinikum rechts der Isar · DEMedizinische Hochschule Hannover · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Infectious complications are a major cause of morbidity and mortality after kidney transplantation. Methods: In this transplant cohort study at the German Center of Infectious Diseases (DZIF), we evaluated all infections occurring during the first year after renal transplantation. We assessed microbial etiology, incidence rates, and temporal occurrence of these infections. Results: Of 804 renal transplant recipients (65.2% male, 51 ± 14 years), 439 (54.6%) had 972 infections within the first year after transplantation. Almost half of these infections (47.8%) occurred within the first 3 months. Bacteria were responsible for 66.4% (645/972) of all infections, followed by viral (28.9% [281/972]) and fungal (4.7% [46/972]) pathogens. The urinary tract was the most common site of infection (42.4%). Conclusions: Renal allograft recipients in Germany experience a high burden of infectious complications in the first year after transplantation. Bacteria were the predominating pathogen, followed by opportunistic infections such as cytomegalovirus. Microbial etiology varied between age groups, and resistant bacteria were identified in 10% of recipients.

Indexed as

cohort studyDZIFGermaninfectionrenal transplantation

Identifiers

PMID35855001
PMCPMC9280327
OpenAlexW4280572313

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.